摘要
目的总结肝硬化并发门静脉血栓(PVT)患者的临床特征并分析PVT形成的危险因素。方法回顾性分析2015年2月~2019年2月我院肝胆包虫科治疗的160例肝硬化患者,分析比较PVT组与未发生PVT组患者临床资料的差异,采用多因素分析发生PVT的危险因素。结果80例PVT患者腹痛、腹水和消化道出血发生率、血小板(PLT)和白细胞(WBC)计数显著高于80例未发生PVT组(P<0.05);经多因素分析,发现PLT计数、糖尿病史和脾切除史为肝硬化并发门静脉血栓形成的独立危险因素(P<0.05)。结论肝硬化并发PVT患者以HGB、PLT、WBC为主要实验室表现,以腹水、下消化道出血、肝功异常为主要临床症状。PLT、糖尿病史和脾切除史为肝硬化并发门静脉血栓的独立危险因素。
Objective The aim of this study was to analyze the clinical characteristics and risk factors of portal vein thrombosis(PVT)in patients with liver cirrhosis(LC).Methods A retrospective analysis was made on 160 patients with LC admitted to our Department in our hospital from February 2015 through February 2019.The clinical symptoms,laboratory indexes and general data of patients were collected.The multivariate Logistic analysis was applied to evaluate the risk factors of PVT.Results The incidence of abdominal pain,ascites and gastrointestinal hemorrhage,and the platelet(PLT)counts and white blood cell(WBC)counts in 80 patients with PVT were significantly higher than those in 80 patients without PVT;the multivariate Logistic analysis showed that the PLT counts,diabetes and splenectomy were the independent risk factors for PVT in patients with LC(P<0.05).Conclusion The ascites,gastrointestinal hemorrhage and liver dysfunction are the main clinical manifestation in patients with LC and PVT,and the PLT counts,diabetes and splenectomy are the main independent risk factors for portal vein thrombosis.
作者
热那特·克力木
吐尔干艾力·阿吉
邵英梅
Rinat·Kirim;Turganaili·Aj;Shao Yinmei(Department of Hepatobiliary Surgery,First Affiliated Hospital,Xinjiang Medical University,Urumqi 830054)
出处
《实用肝脏病杂志》
CAS
2020年第3期401-404,共4页
Journal of Practical Hepatology
基金
新疆维吾尔自治区自然科学基金资助项目(编号:SKL-HIDCA-2017-1)。
关键词
肝硬化
门静脉血栓
血小板
糖尿病
脾切除术
危险因素
Liver cirrhosis
Portal vein thrombosis
Platelets
Diabetes mellitus
Splenectomy
Risk factors
