摘要
目的应用高分辨磁共振血管壁成像技术测量脑干梗死患者梗死体积和基底动脉斑块参数,明确斑块参数与梗死体积的关系。方法收集2017年10月~2018年6月牡丹江医学院附属红旗医院临床初步诊断为脑干梗死的22例患者,进行高分辨磁共振检查。在软件上测得梗死体积、最窄层面管腔面积、最窄层面血管面积、最大管壁厚度、最小管壁厚度,并计算出管壁面积、最窄层面斑块面积、狭窄率、重构指数、斑块负荷及偏心指数。分析各斑块参数与梗死体积之间的相关性。结果纳入分析22例患者的梗死体积为(309.07±253.97)mm^3。最窄层面管腔面积为(4.54±4.13)mm^2,最窄层面血管面积为(15.60±8.04)mm^2。管壁面积为(11.09±4.89)mm^2,最窄层面斑块面积为(3.63±2.81)mm^2。最大管壁厚度为(1.30±0.32)mm,最小管壁厚度为(0.60±0.22)mm,狭窄率为3%~88%。重构模式结果显示,7例为阳性重构,9例为阴性重构,6例未见明显重构,阴性重构与阳性重构同样常见。以偏心模式为主,仅4例表现为向心性模式。Pearson相关性分析结果显示,梗死体积与狭窄率成正相关(r=0.45,P=0.04),与重构指数成负相关(r=-0.47,P=0.03)。结论 3.0 T高分辨磁共振测量基底动脉斑块参数,可用于指导临床治疗及病情监测,有利于改善远期预后。
Objective To measure the infarct volume and basilar artery plaque parameters in patients with brainstem infarction by resolution magnetic resonance imaging of vascular walls, and to determine the relationship between plaque parameters and infarct volume. Methods A total of 22 patients with brainstem infarction initially diagnosed in Hongqi Hospital Affiliated to Mudanjiang Medical University from October 2017 to June 2018 were enrolled for high-resolution magnetic resonance imaging. The infarct volume, lumen area at the narrowest level, vascular area at the narrowest level,maximum wall thickness and minimum wall thickness were measured by software. The wall area, narrowest patch area,stenosis rate, reconstruction index, patch load and eccentricity index were calculated. The correlation between plaque parameters and infarct volume was analyzed. Results The infarction volume of the 22 patients included in the analysis was(309.07±253.97) mm^3, the lumen area at the narrowest level was(4.54±4.13) mm^2, the vascular area at the narrowest level was(15.60±8.04) mm^2, the wall area was(11.09±4.89) mm^2, the plaque area at the narrowest level was(3.63±2.81) mm^2, the maximum wall thickness was(1.30±0.32) mm, the minimum wall thickness was(0.60±0.22) mm, and the stenosis rate was 3%~88%. The results of reconstruction mode showed that 7 cases were positive reconstruction, 9 cases were negative reconstruction, and 6 cases showed no obvious reconstruction. Negative reconstruction was as common as positive reconstruction. Pearson correlation analysis results showed that the infarct volume was positively correlated with the stenosis rate(r=0.45, P=0.04) and negatively correlated with the reconstruction index(r=-0.47, P=0.03). Conclusion 3.0 T high resolution magnetic resonance measurement of basilar artery plaque parameters can be used to guide clinical treatment and disease monitoring, which is conducive to improving long-term prognosis.
作者
卢鑫
杨印东
杨晓帆
陈兰娟
解金金
侯宗易
LU Xin;YANG Yin-dong;YANG Xiao-fan;CHEN Lan-juan;XIE Jin-jin;HOU Zong-yi(Graduate School,Mudanjiang Medical University,Heilongjiang Province,Mudanjiang157011,China;Department of Neurology,Hongqi Hospital Affiliated to Mudanjiang Medical University,Heilongjiang Province,Mudanjiang157011,China)
出处
《中国当代医药》
2020年第10期56-59,共4页
China Modern Medicine
基金
黑龙江省牡丹江市科学技术计划项目(Z2016s0089)。
关键词
脑干梗死
高分辨磁共振
基底动脉
斑块参数
梗死体积
Brain stem infarction
High resolution magnetic resonance
Basilar artery
Plate parameters
Infarct volume
