摘要
目的探讨超声造影对肝脏占位性病变良、恶性鉴别诊断的价值。方法2018年5月至2019年10月对30例肝脏占位性病变病人经外周肘静脉注射造影剂Sono Vue行超声造影检查,依据病变的造影开始增强时间、达峰时间及开始消退时间对其进行良恶性鉴别诊断,并分析不同类型肝脏占位性病变的增强模式。结果以手术或穿刺病理确诊病变类型:恶性病变21个(肝细胞性肝癌14个,胆管细胞性肝癌1个,转移性肝癌6个),以穿刺病理或随访MR/CT临床诊断良性病变11个(肝血管瘤9个,肝脏局灶性结节增生1个,肝硬化结节1个)。超声造影正确诊断恶性病变21个,正确诊断良性病变10个。恶性病变开始增强时间(12.76±2.68 s vs.16.12±3.82 s)、达峰时间(23.18±3.57 s vs.42.78±10.46 s)、开始消退时间(40.69±8.42 s vs.78.35±14.63 s),大部分恶性病变明显早于良性病变,但有小部分不同类型病变间有交叉。结论超声造影对肝脏占位性病变良、恶性的鉴别诊断准确率较高,具有较高的应用价值。
Objective To explore the value of contrast-enhanced ultrasound(CEUS)in the differential diagnosis of benign and malignant liver lesions.Methods From May 2018 to October 2019,30 patients with focal hepatic lesions were performed contrast-enhanced ultrasound(CEUS)examination in our hospital.After SonoVue(a contrast agent)was injected into the peripheral elbow vein,time-to-peak,wash-in time,wash-out time were recorded and made the differential diagnosis of benign and malignant lesions,and the data were statistically analyzed.Results Pathological results from operation or fine-needle aspiration biopsy,21cases with malignant lesions(including 14 HCC,1 cholangiocarcinoma and 6 metastatic HCC),11 cases of benign lesions(9 hemangiomas,1 focal nodular hyperplasia,1 cirrhosis).21 malignant lesions and 10 benign lesions were correctly diagnosed by CEUS.The wash-in time was 12.76±2.68 s vs.16.12±3.82 s,time-to-peak 23.18±3.57 s vs.42.78±10.46 s,wash-out time 40.69±8.42 s vs.78.35±14.63 s between malignant lesions and benign lesions,and in which most of the malignant lesions were earlier than the benign ones.Conclusion CEUS is a very reliable technique with a high sensitivity for the differential diagnosis of benign and Malignant local hepatic lesions.
作者
李雄
蓝思荣
李嘉
许建辉
LI Xiong;LAN Si-rong;LI Jia;XU Jian-hui(Department of Ultrasonography,Meizhou People's Hospital,Meizhou,Guangdong 514031,China;Department of Hepatobiliary Surgery,Meizhou People's Hospital,Meizhou,Guangdong 514031,China)
出处
《岭南现代临床外科》
2020年第2期176-179,共4页
Lingnan Modern Clinics in Surgery
基金
2018年度梅州市社会发展科技计划项目(2018B012)。
关键词
超声造影
肝脏占位性病变
鉴别诊断
contrast-enhanced ultrasound
focal hepatic lesion
differential diagnosis
