摘要
目的探讨辽宁省农村地区卒中复发情况及其相关危险因素,为制定综合有效的卒中二级预防提供依据。方法于2017年9月-2018年5月进行横断面研究,在凌源市、朝阳县、东港市及辽阳县10926名≥40岁的常驻居民进行调查,经过问卷调查、体格检查和实验室检查,分析卒中复发比例及其相关危险因素。结果辽宁省农村地区卒中复发粗率为27.5%(201/731),男女无统计学差异(28.3%vs 26.67%,P>0.05)。标化率为21.76%,男女标化率分别为24.66%及14.9%,男性高于女性。60~90岁人群人群卒中复发率最高,为32.21%。多因素logistic回归分析显示,男性(OR=1.48%、95%CI=1.02~2.14)、高低密度脂蛋白(OR=5.68,95%CI=2.50~12.93)、低高密度脂蛋白(OR=1.93,95%CI=1.08~3.47)、超重或肥胖(OR=1.58,95%CI=1.17~2.42)是卒中复发的主要危险因素,而家庭年收入大于2万元(OR=0.43,95%CI=0.20~0.90)为卒中复发的主要保护性因素。结论辽宁省农村地区卒中复发率较高,卒中复发危险因素较多,疾病负担较重,开展综合有效的脑卒中二级预防是目前亟待解决的难题。
Objective To explore the prevalence and risk factors of stroke recurrence among rural residents in Liaoning province and provide population-based evidences for secondary prevention of stroke.Methods Using stratified cluster random sampling,we recruited 12808 permanent rural residents aged ≥40 years in 19 villages of 4 counties/districts in different geographical regions of Liaoning province.A cross-sectional survey,including questionnaire interview,physical examination and laboratory detection,was carried out to collect the information on stroke recurrence and its associates among the residents between September 2017 and May 2018.Results Among the 10926 participants completing the survey,totally 731 stroke patients were identified.For all the stroke patients,the crude prevalence rate of stroke recurrence was 27.5% and there was no significant difference in the rate between male and female patients(28.3% vs.26.67%,P>0.05);the standardized prevalence rate of stroke recurrence was 21.76%,with a significantly higher rate in the male patients than in the female patients(24.66% vs.14.9%,P<0.05).The highest prevalence rate(32.21%)of stroke recurrence was observed among the patients aged 60-69 years.Multivariate logistic regression analysis demonstrated that male gender(odd ratio[OR]=1.48%,95% confidence interval[95%CI]:1.02-2.14),high low-density lipoprotein cholesterol(OR=5.68,95%CI:2.50-12.93),low high-density lipoprotein cholesterol(OR=1.93,95%CI:1.08-3.47),overweight or obesity(OR=1.58,95%CI:1.17-2.42)were independent risk factors of stroke recurrence;while with a high annual household income(>20000 yuan RMB)was a protective factor against stroke recurrence.Conclusion The prevalence rate of stroke recurrence is high and influence by multiple factors among rural stroke patients aged 40 years and above in Liaoning province,suggesting that comprehensive and effective secondary and tertiary stroke prevention need to be promoted urgently in the population.
作者
庞艳敏
田园梦
井丽
张博强
阎涵
刘爽
刘达
杨佐森
邢立莹
张立敏
PANG Yan-min;TIAN Yuan-meng;JING Li(The First Affiliated Hospital of China Medical University,Shenyang,Liaoning Province 110001,China;不详)
出处
《中国公共卫生》
CAS
CSCD
北大核心
2020年第3期341-345,共5页
Chinese Journal of Public Health
基金
辽宁省重点研发项目(2018225066)
辽宁省“百千万人才工程”资助项目(辽人社[2018]47号)。
关键词
卒中复发
患病率
危险因素
stroke recurrence
prevalence
risk factor