摘要
目的评价中山大学附属江门医院/江门市中心医院住院患者特殊使用级抗菌药物临床应用情况。方法回顾性调查中山大学附属江门医院/江门市中心医院2018年10-12月所有使用特殊级抗菌药物的非儿科患者病历491份,分析限定日剂量数(DDDs)、药物利用指数(DUI),并进行临床用药合理性评价,对不适宜问题进行分类整理。结果注射用美罗培南(0.25 g)的DDDs、DUI最高,分别为1400.38和1.27;总的微生物送检率为85.54%;用药不合理56例次,其中用法用量不适宜(46.43%)和品种选择不适宜(30.36%)为主要问题。结论医院特殊使用级抗菌药物总体应用良好,但也存在一些问题,应继续加强宣传和严格管理,以保护该类药物在治疗严重感染性疾病中的重要地位。
Objective To explore the clinical utilization of antibiotics for special use on patients in Affiliated Jiangmen Hospital of Sun Yat-San University/Jiangmen Central Hospital,analyze and evaluate its medication rationality.Methods A retrospective analysis was made of 491 medical records of all non-pediatric patients using special grade antibacterials in Affiliated Jiangmen Hospital of Sun Yat-San University/Jiangmen Central Hospital from October to December 2018.Defined daily doses(DDDs)and drug utilization index(DUI)were analyzed.The medication rationality of carbapenems was evaluated and inappropriate cases were also classified and analyzed statistically.Results The meropenem for injection(0.25 g)had the highest DDDs and DUIs of 1400.38 and 1.27,respectively.The total rate of microbial inspection was85.54%.There were 56 cases of irrational use records,in which,irrational dosage(46.43%)and improper drug selection(30.36%)were the major problems.Conclusion The antibiotics for special use are generally well applied in the hospital,but there were still some problems.We should continue to strengthen publicity and strict management to protect the important position of this class of drugs in the treatment of serious infectious diseases.
作者
冯志平
于思源
FENG Zhiping;YU Siyuan(Department of Pharmacy,Affiliated Jiangmen Hospital of Sun Yat-San University/Jiangmen Central Hospital,Guangdong Province,Jiangmen 529000,China)
出处
《临床合理用药杂志》
2020年第7期1-2,5,共3页
Chinese Journal of Clinical Rational Drug Use
