摘要
目的对比不同手术方式对子宫肌瘤患者临床疗效及内分泌状态的影响。方法将四川省绵阳市中医医院2018年1月-2019年2月收治的90例子宫肌瘤患者依据手术方式差异分为A、B、C三组,每组各30例,A组采用腹腔镜下子宫肌瘤剥除术,B组采用子宫次全切除术,C组采用子宫全切除术,对比三组手术效果及手术前后内分泌指标变化。结果相比其他两组,A组的术中出血量最少,手术时间耗时最短,差异显著(P<0.05),但在术后住院时间三组患者无显著差异(P>0.05),且三组手术效果相比差异无统计学意义(P>0.05);术前各组间各项内分泌指标比较不存在统计学差异(P>0.05);术后随访半年,B组和C组E2水平明显低于术前,FSH、LH高于术前,组间对比发现,术后A组E2明显高于B组和C组,FSH、LH低于其他两组,差异有统计学意义(P<0.05)。结论三种手术均能达到理想的手术效果,但采用腹腔镜下子宫肌瘤剥除术对子宫肌瘤患者的内分泌状态影响更小,手术安全性更高。
Objective To compared the effects on different surgical methods on the clinical efficacy and endocrine status of patients with uterine fibroids.Methods 90 patients with uterine fibroids admitted to Mianyang Hospital of Traditional Chinese Medicine from January 2018 to February 2019 were selected and were divided into groups A,B and C according to the different surgical methods,with 30 patients in each group.Group A was treated with laparoscopic myomectomy,group B were underwent subtotal hysterectomy,and group C were underwent total hysterectomy.The results of operation and the change of endocrine index before and after operation were compared.Results Compared with the other two groups,group A had the lowest intraoperative blood loss and the shortest operative time,with a significant difference(P<0.05).However,there was no significant difference in postoperative hospitalization time and operative effect among the three groups(P>0.05).There was no statistically significant difference in each endocrine index among the groups before surgery(P>0.05).After six months of follow-up,level of E2 in group B and group C was significantly lower than that before surgery,and FSH and LH were higher than that before surgery.The comparison among groups showed that postoperative E2 in group A was significantly higher than that in group B and group C,and FSH and LH were lower than the other two groups,with statistically significant differences(P<0.05).Conclusion All of the three operations can achieve ideal results,but laparoscopic myomectomy has less impact on the endocrine status of patients with uterine fibroids and higher surgical safety.
作者
郑瑜
ZHENG Yu(Department of Obstetrics and Gynecology,Mianyang Hospital of Traditional Chinese Medicine,Mianyang Sichuan 621000,China)
出处
《临床研究》
2020年第5期62-64,共3页
Clinical Research
