摘要
目的探讨肺康复运动训练对非手术老年非小细胞肺癌(NSCLC)患者肺功能、运动耐受力及生活质量的影响。方法选取60例非手术老年NSCLC患者,依据患者康复运动方式不同分为肺康复运动组(n=36)和常规康复组(n=24),常规康复组患者实施常规康复治疗,肺康复运动组患者在此基础上实施肺康复运动训练,共治疗4周。比较两组患者肺功能指标[肺活量占预计值百分比(VC%)、第一秒用力呼气容积占预计值百分比(FEV1%)、用力肺活量占预计值百分比(FVC%)]、血气指标[动脉血氧分压(PaO2)、动脉血二氧化碳分压(PaCO2)]、运动耐受力[6分钟内的步行距离(6MWTD)、呼吸困难指数(MMRC)、BODE指数]及生活质量。结果治疗4周后,肺康复运动组患者VC%、FEV1%、FVC%、PaO2均高于常规康复组患者,6MWTD长于常规康复组患者,PaCO2、MMRC、BODE均低于常规康复组患者,差异均有统计学意义(P﹤0.05)。肺康复运动组患者躯体功能、角色功能、情绪功能、认知功能、社会功能及总体健康状况评分均高于本组治疗前和常规康复组患者,差异均有统计学意义(P﹤0.05)。结论非手术老年NSCLC患者常规治疗后进行肺康复运动训练能够有效改善肺功能及血气指标,提高运动耐受性,改善生活质量及预后。
Objective To investigate the effect of pulmonary rehabilitation on the pulmonary function,exercise tolerance and quality of life in elderly patients with non-small cell lung cancer(NSCLS)with non-operative management.Method A retrospective analysis was performed on 60 elderly patients with NSCLC treated with non-operative management,who were divided into pulmonary rehabilitation group(n=36)and routine rehabilitation group(n=24)according to the mode of rehabilitation interventions given.Patients in both groups were administered with routine rehabilitation therapy,and additional pulmonary rehabilitation was prescribed for pulmonary rehabilitation group,lasting for 4 weeks.Pulmonary function indicators[percentage of vital capacity to predicted value(VC%),percentage of forced expiratory volume in one second to predicted value(FEV1%),percentage of forced vital capacity to predicted value(FVC%)],blood gas indexes[partial pressure of arterial oxygen(PaO2),partial pressure of carbon dioxide(PaCO2)],exercise tolerance[6 minute walk test distance(6MWTD),modified medical research council(MMRC),BODE index]and quality of life(QOL)were compared between the two groups.Result After 4 weeks of treatment,the VC%,FEV1%and FVC%in pulmonary rehabilitation group were significantly higher than those in the routine rehabilitation group(P<0.05),with longer 6MWTD and lower PaO2,MMRC and BODE index than in those with routine interventions(P<0.05).The scores of physical function,role function,emotional function,cognitive function,social function and overall health status in the pulmonary rehabilitation group were significantly improved after treatment,and were evidently higher than those in the routine rehabilitation group(P<0.05).Conclusion Pulmonary rehabilitation helps improve the pulmonary function,blood gas index and ameliorate exercise tolerance of elderly patients with NSCLC that are under non-operative management,thereby improving the quality of life of the patients.
作者
马静
马胜利
王进菊
MA Jing;MA Shengli;WANG Jinju(Department of Rehabilitation Medicine,Xinyang Central Hospital,Xinyang 464000,He’nan,China)
出处
《癌症进展》
2020年第6期631-634,共4页
Oncology Progress
关键词
肺康复运动训练
非小细胞肺癌
非手术
运动耐受力
pulmonary rehabilitation
non-small cell lung cancer
non-operative
exercise tolerance
