摘要
目的探讨脂蛋白相关磷脂酶A2(Lp-PLA2)和同型半胱氨酸(Hcy)检测在健康体检中的意义。方法回顾性分析469名健康体检者Lp-P LA2、Hcy水平,分别比较Lp-PLA2、Hcy正常组和异常组中常规生化指标(血脂、肾功能、血糖)的差异性;分析二者与常规生化指标的相关性。结果Lp-PLA2正常组与异常组比较,性别比例、TC、TG、VLDL-C、Lpa和Lp-PLA2差异有统计学意义(P<0.05);Hcy正常组与异常组比较,性别比例、LDL-C、血糖和Hcy差异有统计学意义(P<0.05);Lp-PLA2与TC、LDL-C和APoB存在相关性(P<0.05),Hcy与TC和APoB存在相关性(P<0.05),而Lp-PLA2和Hcy无相关。结论Lp-PLA2和Hcy结合常规实验室指标应用于健康人群定期体检,能够起到早期预防、排除潜在心血管疾病的重要作用。
Objective To investigate the significance of detection of lipoprotein-associated phospholipase A2(Lp-PLA2)and homocysteine(Hcy)in health examination.Methods The levels of Lp-PLA2 and Hcy in 469 healthy subjects were retrospectively analyzed,and the differences of routine biochemical indicators(blood lipid,renal function,blood sugar)between normal and abnormal groups of Lp-PLA2 and Hcy were compared,and the correlation between them and routine biochemical indicators was analyzed.Results There were significant differences in sex ratio,triglyceride(TG),total cholesterol(TC),very low density lipoprotein(VLDL-C),Lpa and Lp-PLA2 between Lp-PLA2 normal group and abnormal group(P<0.05).There were significant differences in sex ratio,low density lipoprotein(LDL-C),Glu and Hcy between Hcy normal group and abnormal group(P<0.05);Lp-PLA2 was correlated with TC,LDL-C and apolipo-protein B(ApoB)(P<0.05).Hcy was correlated with TC,LDL-C and ApoB(P<0.05).There is no correlation between Lp-PLA2 and Hcy.Conclusion Lp-PLA2 and Hcy combined with routine laboratory indicators can play an important role in early prevention and elimination of potential cardiovascular diseases in healthy people.
作者
潘丽
丁怡文
芮黎
李东
杨宇溪
潘宝龙
Pan Li;Ding Yiwen;Rui Li;Li Dong;Yang Yuxi;Pan Baolong(Laboratory Department of Yuxi People's Hospital,Yunnan 653100,China;不详)
出处
《实用医技杂志》
2020年第2期163-166,共4页
Journal of Practical Medical Techniques
关键词
磷脂酶A2
半胱氨酸
脂蛋白脂酶
肾功能试验
血糖
Phospholipase A2
Cysteine
Lipoprotein lipase
Kidney function tests
Blood glucose
