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探讨硝普钠联合多巴胺治疗急性心力衰竭的疗效 被引量:2

To Investigate The Efficacy of Sodium Nitroprusside Combined With Dopamine in The Treatment of Acute Heart Failure
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摘要 目的 采用硝普钠联合多巴胺治疗急性心力衰竭的疗效观察.方法 选取2016年3月—2019年4月在医院进行急性心力衰竭治疗的98例患者,将98例患者随机分为观察组和对照组,每组各49例,观察组采用硝普钠治疗,对照组采用硝普钠联合多巴胺治疗,分析两组患者的胱抑素C(CysC)、尿微量水平变化及总有效率.结果 观察组胱抑素C(CysC)、β2微球蛋白(β2-MG)、α1微球蛋白(α1-MG)等各项指标都优于对照组,组间数据具有统计学意义(P<0.05);观察组患者的总有效率为95.92%,对照组总有效率为81.63%,组间数据具有统计学意义(P<0.05).结论 在治疗急性心力衰竭的过程中,采用硝普钠联合多巴胺治疗效果更好,有广泛应用的价值. Objective To observe the effect of sodium nitroprusside combined with dopamine in the treatment of acute heart failure.Methods 98 patients with acute heart failure treated in our hospital from March 2016 to April 2019 were randomly divided into two groups:observation group and control group.Each group had 49 cases.The observation group was treated with sodium nitroprusside,while the control group was treated with sodium nitroprusside and dopamine.The changes of cystatin C,urine micro level and total effective rate of the two groups were analyzed.Results cystatin C(Cys C),β2 microglobulin(β2-MG),α1 microglobulin(α1-MG)and other indexes in the observation group were superior to those in the control group,with statistical significance(P<0.05);the total effective rate in the observation group was 95.92%,and that in the control group was 81.63%,with statistical significance(P<0.05).Conclusion In the treatment of acute heart failure,sodium nitroprusside combined with dopamine is more effective and has wide application value.
作者 王冰 刘伟昌 李静 任兴帅 WANG Bing;LIU Weichang;LI Jing;REN Xingshuai(Department of Cardiology,People’s Hospital of Zouping Shandong,Binzhou Shandong 256200,China;Medical Services,People’s Hospital of Zouping Shandong,Binzhou Shandong 256200,China)
出处 《中国继续医学教育》 2020年第10期120-122,共3页 China Continuing Medical Education
关键词 硝普钠 多巴胺 急性心力衰竭 胱抑素C Β2微球蛋白 Α1微球蛋白 sodium nitroprusside dopamine acute heart failure cystatin C β2 microglobulin α1 microglobulin
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