摘要
目的探讨血培养阳性的老年患者降钙素原(PCT)、白细胞计数(WBC)、中性粒细胞比例(Neu%)、超敏C反应蛋白(hs-CRP)的水平变化及临床意义。方法选取2017年1月至2018年6月于本院老年病室住院的老年血培养阳性的112例患者为研究对象,根据患者感染不同的病原菌,分为革兰阳性球菌组、革兰阴性杆菌组及真菌组,根据患者的不同预后分为好转组和恶化组。观察不同病原菌感染率的差异,比较不同感染组患者的PCT、WBC、Neu%、hs-CRP水平,观察不同病原菌患者预后的差异。结果112例血培养阳性患者中,革兰阳性球菌感染53例(47.32%),革兰阴性杆菌感染48例(42.86%),真菌感染11例(9.82%);不同病原菌感染后血清PCT、WBC、Neu%、hs-CRP的升高水平从高到低分别为革兰阴性杆菌组、真菌组、革兰阳性球菌组,预后比较,恶化率分别为革兰阳性球菌组(22.6%)、革兰阴性杆菌组(16.7%)和真菌组(63.6%),差异具有统计学意义(c2=10.909,P=0.004)。结论血培养阳性的老年患者血清中PCT、WBC、Neu%、hs-CRP水平会升高,且升高的程度、预后与不同病原菌感染存在密切相关性。
Objective To investigate the changes and clinical significance of procalcitonin(PCT),WBC,neutrophil proportion(Neu%),hyersensitive c-reactive protein(hs-CRP)in elderly patients with positive blood culture.Methods A total of 112 patients with positive blood cultures who were admitted to the geriatric ward of our hospital from January 2017 to June 2018 were selected as the research subjects,according to the different pathogens of infected patients,it can be divided into gram-positive cocci,gram-negative bacillus group and fungi group,according to the different outcomes of patients with,will be divided into the improvement group and deterioration group.To observe the difference in infection rate of different pathogenic bacteria,and compare the differences in PCT,WBC,Neu%and hs-CRP levels of patients in different infection groups,and observe the difference in prognosis of patients with different pathogenic bacteria.Results Of the 112 patients with positive blood culture,53(47.32%)were infected with gram-positive cocci,48(42.86%)were infected with gram-negative bacilli,and 11(9.82%)were infected with fungi.Different pathogenic bacteria infection after serum PCT,the rise of the WBC,Neu%,hs-CRP level from high to low were gram-negative bacillus group,the fungus,gram-positive cocci,prognosis,deterioration rate respectively group(22.6%)were gram positive coccus,gram-negative bacillus group(16.7%)and fungi(63.6%),the difference was statistically significant(c2=10.909,P=0.004).Conclusion This study showed that the serum PCT,WBC,Neu%and hs-CRP levels were higher in elderly patients with positive blood culture,and the increased degree and prognosis were closely related to different pathogenic bacteria infection.
作者
谭志霞
彭建宏
朱霞东
Tan Zhixia;Peng Jianhong;Zhu Xiadong(Changsha Psychiatric Hospital,Changsha,Hunan,410004,China)
出处
《当代医学》
2020年第11期5-7,共3页
Contemporary Medicine
关键词
老年患者
血培养
降钙素原
白细胞计数
超敏C反应蛋白
Elderly patients
Blood culture
Procalcitonin
White blood cell count
Hypersensitive c-reactive protein
