摘要
上尿路尿路上皮癌(upper tract urothelial carcinoma,UTUC)是一种在西方国家相对少见的肿瘤,约占尿路上皮癌的5%,而UTUC在中国的发病率远高于西方国家。近年来对UTUC预后分子的研究有较大的进展,包括Ki-67,P53和HER-2等在肿瘤病理实践中被广泛应用的分子,还有不少有应用前景的膜受体和信号转导分子,以及一些近期较热门的分子,如PD-1和PDL-1等。
Upper tract urothelial carcinoma(UTUC)is a relatively rare tumor in western countries,accounting for 5%of urothelial carcinoma,while the incidence of UTUC in China is much higher than that in western countries.In recent years,great progress has been made in the study of prognostic molecular of UTUC,including Ki-67,P53 and HER-2,which are widely used in pathological practice,as well as many promising membrane receptors,signal transduction molecules,and some popular molecules,such as PD-1 and PD-L1.
作者
吴西抗(综述)
贺慧颖(审校)
WU Xikang;HE Huiying(Department of Pathology,Peking University Health Science Center/Peking University Third Hospital,Beijing 100083,China)
出处
《临床与病理杂志》
2020年第3期734-742,共9页
Journal of Clinical and Pathological Research
关键词
上尿路尿路上皮癌
肿瘤进展
预后分子
upper tract urothelial carcinoma
tumor progression
prognostic factors
