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阿替普酶静脉溶栓治疗致腰骶部血管性水肿1例

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摘要 血管性水肿是皮肤或黏膜下毛细血管扩张引起的急性局限性水肿,是过敏反应的严重表现,而药物导致的过敏反应占到住院患者死亡原因的20%[1],尤其应引起重视。阿替普酶即重组人组织型纤维蛋白溶酶原激活剂(rt-PA)作为神经内科常用治疗急性缺血性卒中(AIS)的静脉溶栓药物,在临床用药中也可能出现过敏反应,最常见的是口舌部血管性水肿(OA),严重者可危及生命安全[2]。国内已有rt-PA相关OA的病例报道[3-4],但未见应用rt-PA静脉溶栓后出现腰骶部血管性水肿的病例报道。现报道本院神经内科发生的1例患者,便于基层临床医生对rt-PA相关血管性水肿有更多的认识。
作者 邓杉杉 滕元
出处 《现代医药卫生》 2020年第7期1116-1118,共3页 Journal of Modern Medicine & Health
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