摘要
为了找出涉及网络成瘾(IAD)机制的关键脑区,同时探查IAD者脑功能和结构特征,招募IAD组和对照组大学新生被试,扫描和比较分析静息态功能磁共振和结构磁共振数据.结果表明:网络成瘾者的右枕叶和右舌回的静息态脑自发活性呈亢进,左眶额叶呈降低;右海马旁回、右枕叶和右舌回的皮层灰质密度显著降低;右枕叶的功能和结构异常水平都与网络成瘾量表(IAT)分显著相关.右枕叶在网络成瘾的发病机制中的作用值得进一步探察.
In order to identify the key brain regions involved in the mechanism of internet addiction disorder(IAD)and investigate the functional and structural characteristics of the people with IAD,the IAD group and control group of first-year university students were recruited,the resting-state functional magnetic resonance and structural magnetic resonance data of these students were scanned and comparatively analyzed.In the IAD group,the results presented the hyperfunction in the resting-state brain spontaneous activity of the right occipital lobe and right lingual cortex,the reduction in the left orbitofrontal cortex(OFC),as well as the decreasing cortical grey matter density in the right parahippocampal gyrus,right occipital lobe and right lingual cortex.The functional and structural abnormalities of the right occipital lobe were significantly correlated with IAD level.The role of right occipital lobe in the pathogenesis of IAD deserved further investigation.
作者
韩岱
李梅
梅敏君
孙小菲
朱春莹
HAN Dai;LI Mei;MEI Minjun;SUN Xiaofei;ZHU Chunying(Institutes of Psychological Sciences,Hangzhou Normal University,Hangzhou 311121,China;Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments,Hangzhou 311121,China;Psychiatry Department,The Affiliated Hospital of Hangzhou Normal University,Hangzhou 310015,China;Mental Health Education and Counseling Center,Hangzhou Normal University,Hangzhou 311121,China)
出处
《杭州师范大学学报（自然科学版）》
CAS
2020年第2期132-138,共7页
Journal of Hangzhou Normal University(Natural Science Edition)
基金
浙江省自然科学基金项目(LQ14H090004)
国家留学基金项目(201708330165).
关键词
网络成瘾
低频振荡振幅(ALFF)
基于体素的形态学(VBM)
右枕叶
internet addiction disorder
amplitude of low-frequency fluctuation(ALFF)
voxel-based morphometry(VBM)
right occipital lobe
