摘要
肝异型增生结节(dysplastic nodule,DN)是肝内结节样占位病变,具有较高的恶变风险,被视为肝细胞癌的癌前病变。尽早诊断DN并随访能有效发现早期肝癌。影像学检查是目前临床诊断DN的常用方法。常规超声、CT、MR诊断效果有限;超声造影、增强CT、增强MR能区分部分DN与HCC,临床仍需要联合两种或两种以上检查以确诊。普美显增强MRI等新型分子影像学检查对于DN的诊断有较好的特异性,将成为未来的发展方向。
Hepatic dysplastic nodule(DN)is an intrahepatic nodular lesion with a high risk of carcinogenesis.DN is considered as a precancerous lesion of hepatocellular carcinoma(HCC).Early diagnosis of DN and follow-up are effective approaches to detect early HCC.Imaging examination is a common method for diagnosing DN.The usage of conventional ultrasound,conventional CT and MR for diagnosing DN is limited.CEUS,enhanced CT and enhanced MR can distinguish partial DN from HCC.Two or more examinations are often required to establish a clinical diagnosis.Novel molecular imaging such as Gd-EOB-DTPA-enhanced MRI have a good specificity for the diagnosis of DN,which will become the future development direction.
作者
王昕昱
王征
Wang Xinyu;Wang Zheng(Department of Liver Surgery,Zhongshan Hospital,Fudan University,Shanghai 200032,China)
出处
《影像研究与医学应用》
2020年第7期2-4,共3页
Journal of Imaging Research and Medical Applications
关键词
肝细胞癌
异型增生结节
影像诊断
Hepatocellular carcinoma
Dysplastic nodule
Imaging diagnosis
