摘要
目的:探讨转铁蛋白(TRF)、C反应蛋白(CRP)对早期新生儿生理和病理性黄疸的鉴别诊断意义。方法:选取2018年6-9月在本院住院的50例病理性黄疸新生儿临床资料为病例组,并选取同时期50例生理性黄疸新生儿临床资料为对照组,进行回顾性分析。比较两组出生后24 h内、1周、2周的血清总胆红素(TBIL)、C反应蛋白(CRP)、转铁蛋白(TRF)水平,并对发生病理性黄疸危险因素进行分析。结果:出生后24 h内、1周、2周,病例组TBIL与CRP水平均明显高于对照组,而TRF水平均明显低于对照组(P<0.05);血清CRP、TRF为病理性黄疸的危险因素(P<0.05)。结论:TRF、CRP对早期新生儿生理和病理性黄疸的鉴别诊断具有重要意义。
Objective: To investigate the significance of transferrin(TRF) and C-reactive protein(CRP) in the differential diagnosis of early neonatal physiology and pathological yellow blood. Method: The clinical data of 50 pathologically jaundice neonates hospitalized in our hospital from June to September 2018 were selected as the case group, and the clinical data of 50 physiology jaundice neonates in the same period were selected as the control group for retrospective analysis. Serum total bilirubin(TBIL), C-reactive protein(CRP) and transferrin(TRF) levels were compared between the two groups within 24 h, 1 week and 2 weeks after birth, and the risk factors of pathological yellowing were analyzed. Result: Within 24 h, 1 week and 2 weeks after birth, TBIL and CRP levels in the case group were significantly higher than those in the control group, while TRF were significantly lower than those in the control group(P<0.05). Serum CRP and TRF were risk factors for pathologic jaundice(P<0.05). Conclusion: TRF and CRP are important in the differential diagnosis of early physiological and pathological jaundice in neonates.
作者
林佳燕
洪钦明
王卿
黄晓彬
LIN Jiayan;HONG Qinming;WANG Qing;HUANG Xiaobin(Rongcheng District Maternal and Child Health Hospital,Jieyang 522000,China)
出处
《中国医学创新》
CAS
2020年第2期113-116,共4页
Medical Innovation of China
基金
揭阳市医学科学技术研究立项项目(揭市卫[2019]66号-106)。
