摘要
目的探讨老年维持性透析肾性骨病患者采用血液透析联合血液灌流治疗的效果与价值。方法选取青海省交通医院在2017年1月至2019年8月收治的老年维持性透析肾性骨病患者48例,依循简单随机数字法将患者分为两组,每组24例。对照组行单纯血液透析治疗,实验组在血液透析基础上联合血液灌流治疗。血透联合灌流治疗5次后,统计两组的炎性因子、血清甲状旁腺素(PTH)、骨形态发生蛋白(BMP)水平及不良反发生率,进行对比分析。结果实验组炎性因子、PTH水平低于对照组(P<0.05),BMP水平高于对照组(P<0.01),两组不良反应发生率比较差异无统计学意义(P>0.05)。结论在老年维持性透析肾性骨病的治疗过程中采用血液透析联合血液灌流治疗对炎性因子、PTH的清除,BMP的提升有明显的治疗效果,且不良反应发生率与单纯血液透析一致,值得临床推广。
Objective To study the elderly maintenance dialysis patients with renal sexual bone disease treated by hemodialysis union blood perfusion.Methods A total of 48 elderly patients with renal bone disease undergoing maintenance dialysis admitted to qinghai provincial traffic hospital from January 2017 to August 2019 were selected,and the patients were randomly divided into two groups,each with 24 cases.The control group received hemodialysis alone,while the experimental group received hemoperfusion on the basis of hemodialysis.After 5 times of treatment,inflammatory factors,serum parathyroid hormone(PTH),bone morphogenetic protein(BMP)levels and adverse adverse events in the two groups were counted for comparative analysis.Results After treatment work,experimental inflammatory factor PTH level is relatively lower than control(P<0.01),BMP levels higher than the control group(P<0.01),the incidence of adverse reactions to no difference between the two groups(P>0.05).Conclusion In elderly maintenance hemodialysis treatment of renal osteopathy adopted in the process of hemodialysis union blood perfusion treatment of inflammatory factor of eliminating PTH,BMP ascension has obvious therapeutic effect,and the incidence of adverse reactions are consistent with pure hemodialysis,worth clinical promotion.
作者
王积福
WANG Jifu(Qinghai Provincial Traffic Hospital,Xining,Qinghai 810008,China)
出处
《大医生》
2019年第19期82-83,共2页
Doctor
关键词
维持性透析肾性骨病
血液透析联合血液灌流治疗
治疗效果
maintenance dialysis renal osteopathy
hemodialysis combined with hemoperfusion
therapeutic effect
