摘要
目的:在认知评估量表中划销试验简便易行,多用来评定儿童的注意力,本文探讨将划销试验用于成年人认知功能注意力筛查的可行性。方法:对有记忆力下降主诉的成年受试者同时应用划销试验、临床痴呆评定量表(CDR)、简易精神状态量表(MMSE)、蒙特利尔认知评估量表(MoCA)进行认知功能评估。按CDR评估结果将受试者分为认知功能正常组、非常轻认知功能下降(VM)组、轻度认知功能下降(M)组、中度认知功能下降(Mo)组、重度认知功能下降(S)组。划销试验的结果以注意持久指数作为评价。结果:共纳入515例受试者。注意持久指数在认知正常组明显高于认知功能下降组(P<0.05)。注意持久指数在轻、中和重度认知功能下降组之间无明显差异(P>0.05)。注意持久指数与MMSE、MoCA、CDR评测结果均为中度相关(P<0.05)。以注意持久指数0.3856为认知正常和认知功能下降的分界值时,灵敏度和特异度分别为85.3%和45.3%。结论:划销试验简便易行,能敏感地发现认知功能下降,可用于认知功能早期筛查。
Objective Cancellation test is easy and feasible to performance in cognitive evaluation,which is usually used to assess attention ability in children.We explored the feasibility of cancellation test in adult cognitive evaluation.Methods Adult subjects with complaint of memory decline in the department of Neurology,Tsinghua Yuquan Hospital were enrolled and examined with cancellation test,clinical dementia rating(CDR),mini mental state examination(MMSE)and Montreal cognitive assessment(MoCA)at the same time from January 2014 to December 2018.The subjects were slipped into normal cognition,cognitive mild impairment,dementia(including mild dementia,moderate dementia and serious dementia)groups according to their CDR score.Results A total of 515 subjects were included in this study,including 227 males and 288 females.245 subjects finished more than or 12 years of education and 270 subjects less than 12 years of education.Cancellation index was presented as the results of cancellation test.Cancellation index was significant higher than it was in cognitive impairment group(P<0.05).However,there was no significant difference among mild/moderate/serious dementia groups(P>0.05).Cancellation index was moderately correlated with the scores of MMSE,MoCA and CDR(P<0.05).According to ROC curve,the sensitivity and specify of cancellationtest was 85.3%and 45.3%,respectively with attention index as 0.3856.Conclusion Cancellationtest is easy and feasibility to detect cognitive impairment sensibility,which can be used for early screening of cognitive function.
作者
王静
黄静芬
赵忙所
黄方杰
周世梅
魏妍
石冰心
韩翠石
乔立艳
Wang Jing;Huang Jing-fen;Zhao Mang-suo;Huang Fang-jie;Zhou Shi-mei;Wei Yan;Shi Bing-xin;Han Cui-shi;Qiao Li-yan(Department of Neurology,Tsinghua University Yuquan Hospital)
出处
《阿尔茨海默病及相关病杂志》
2020年第1期31-36,5,共7页
Chinese Journal of Alzheimer's Disease and Related Disorders
关键词
认知功能下降
划销试验
认知筛查
注意力
cognitive impairment
cancellation test
cognitive screening
attention
