摘要
目的探讨≤50岁男性与绝经前女性骨密度低于同龄人平均范围患者的患病率、骨量变化特点与主要临床流行病学特征分布,为其防治提供依据。方法采用美国HOLOGIC,Discovery-Wi型双能X线骨密度仪,对2100例受试者行腰椎与髋关节骨密度检查,并根据年龄把患者分成A、B、C、D四组,对骨密度检查结果与临床资料进行分析。②采用WHO亚洲人骨质疏松诊断标准,Z>-2.0为骨密度在同龄人范围内,Z≤-2.0为骨密度低于同龄人平均范围。结果2100例受试者骨密度在同龄人范围内患者1683例(80.14%,1683/2100),骨密度低于同龄人平均范围受试者417例(19.86%,417/2100)、其中男性214例(24.24%,214/883)、女性203例(16.68%,203/1217),两者患病率对比P<0.05。②≤50岁男性骨密度低于同龄人平均范围者,营养不良性疾病61例、肾脏功能性病变43例、风湿性疾病33例、糖尿病33例、手术后22例、骨质疏松复查72例等;绝经前女性骨密度低于同龄人平均范围者,营养不良性疾病62例、手术后47例、肾脏功能性病变31例、甲状腺疾病25例、系统性红斑狼疮23例,骨质疏松复查65例等。结论50岁男性骨密度低于同龄人平均范围患病率比绝经前女性高,不同性别腰椎与髋关节骨密度水平不同,主要临床流行病学特征分布不同,应根据其特点对患者进行积极预防。
Objective To investigate the prevalence of osteoporosis,bone mass change,and distribution of main clinical epidemiological features in men under 50 years old and premenopausal women with bone mineral density(BMD)scores lower than average level,and to provide evidence for the prevention and treatment of osteoporosis.Methods BMD of the lumbar vertebrae and the hip was detected using a HOLOGIC DEXA machine.BMD result and the clinical data of 2100 patients were analyzed based on A,B,C,and D age groups.(2)WHO Asian diagnostic criteria for osteoporosis were applied.BMD score Z>-2.0 SD was normal and Z≤-2.0 SD was below the average in the same age group.Results Among the 2100 cases,80.14%(1683/2100)had BMD score within the range of the same age people,and 19.86%(417/2100)had BMD score lower than the range of the same age people.In those who had lower BMD,214 cases were males(24.24%)and 203 cases were females(16.68%,P<0.05).(2)In those men who were less than 50 years old and had lower BMD score,61 cases had malnutrition,43 cases had functional kidney disease,33 cases had rheumatoid disease,33 cases had diabetes,22 cases had surgery,and 72 cases had osteoporosis.In premenopausal women who had lower BMD score,62 cases had malnutrition,47 cases had surgery,31 cases had functional kidney disease,25 cases had thyroid disease,23 cases had SLE,and 65 cases had osteoporosis.Conclusion The prevalent rate of low BMD is higher in men less than 50 years old than in premenopausal women(P<0.05).The characteristics of bone mass change in the lumbar vertebrae and the hip and main clinical epidemiological features are different between different genders.The active prevention should be carried out based on the clinical epidemiological features.
作者
高登发
朱燕明
官剑武
周世擎
徐正扬
GAO Dengfa;ZHU Yanming;GUAN Janwu;ZHOU Shiqing;XU Zhengyang(Department of Radiology,the First Medical Center of Chinese PLA General Hospital,Beijing 100853,China)
出处
《中国骨质疏松杂志》
CAS
CSCD
北大核心
2020年第3期333-336,352,共5页
Chinese Journal of Osteoporosis
关键词
骨密度
骨密度低于同龄人平均范围
骨质疏松
继发性骨质疏松
Z值
bone mineral density
bone mineral density below average in the same age
osteoporosis
secondary osteoporosis
Z-score
