摘要
目的:探究MRI常规序列及扩散序列DWI定量参数ADC值在新生儿低血糖脑损伤中的诊断价值。方法:收集整理我院新生儿科2016年6月--2019年1月低血糖脑损伤患儿的临床、影像及检验资料共48例。分析其MRI表现,并根据新生儿低血糖程度分为3个组(a组血糖≤1.0 mmol/L,b组>1.0~1.7 mmol/L,c组>1.7~2.0 mmol/L),应用SPSS 23.0软件分析ADC值在不同分组间的差异及与血糖的相关性。结果:①统计结果:a组17例,b组17例,c组14例;其中28例(58%)在DWI中病灶显示明显优于常规序列(T,WI.T,WI);②不同低血糖严重程度分组(a,b,c)间的ADC值不同,随着低血糖严重程度增加,ADC值呈减低趋势,差异具有统计学意义(P<0.01);③ADC值与低血糖严重程度呈中等程度相关,相关系数r为0.761。结论:①DWI较MRI常规序列能更敏感地发现低血糖脑损伤的部位、范围及损伤程度;②磁共振扩散成像定量参数ADC值在评估新生儿低血糖脑损伤的严重程度中有较好的诊断价值。
Objective:To explore the diagnostic value of conventional MRI sequence and ADC value of DWI in neonatal hypoglycemic brain injury.Methods:A total of 48 cases of neonatal hypoglycemic brain injury were included with complete clinical,imaging and laboratory data from June 2016 to January 2019 in our hospital.The MRI findings were analyzed,and we divided the 48 cases into 3 groups according to the blood glucose level(group a:≤1.0 mmol/L,group b:>1.0~1.7 mmol/L,group c:>1.7~2.2 mmol/L).We use SPSS 23.0 software to analyze the difference of ADC values among different groups and the correlation with blood glucose.Results:①There were 17 patients in group a,17 patients in group b,and 14 patients in.group c.Among them,lesions of 28(58%)were more obviously showed in DWI than in conventional sequences(T,WI,T,WI).②The ADC values were different among different groups(a,b,c).As the severity of hypoglycemia increased,the ADC value decreased,and the difference was statistically significant(P<0.01).③The ADC value was strongly correlated with the severity of hypoglycemia,and the correlation ceffcient r was 0.761.Conclusion:DWI is more sensitive in showing the location,extent and severity to hypoglycemic brain injury than MRI routine sequences.ADC value plays an important role in evaluating the severity of neonatal hypoglycemic brain injury.
作者
谢辉
兰为顺
杨文忠
余旭东
袁先宏
刘萍
XIE Hui;LAN Wei-shun;YANG Wen-zhong;YU Xu-dong;YUAN Xian-hong;LIU Ping(Department of Radiology,Hubei Maternal and Children's Hospital,W uhan 430070,China)
出处
《中国临床医学影像杂志》
CAS
2020年第3期159-162,共4页
Journal of China Clinic Medical Imaging
关键词
脑损伤
低血糖症
婴儿
新生
磁共振成像
Brain injuries
Hypoglycemia
Infant,newborn
Magnetic resonance imaging
