摘要
目的分析心理干预对老年非小细胞肺癌(NSCLC)患者心理状态及生活质量的影响。方法根据干预措施的不同将101例NSCLC患者分为干预组(n=51)和对照组(n=50)。对照组患者接受化疗常规化疗方案,给予生活和一般心理指导,干预组患者在对照组的基础上联合心理干预。干预前后,采用焦虑自评量表(SAS)及抑郁自评量表(SDS)评估两组患者的焦虑状态和抑郁状态,采用欧洲癌症研究与治疗组织(EORTC)生活质量核心30问卷调查(QLQ-C30)和卡氏功能状态(KPS)评分评估两组患者的生活质量。结果干预后,干预组患者SDS评分低于干预前,对照组患者SAS、SDS评分均低于本组干预前和干预组患者,差异均有统计学意义(P<0.05)。干预后,两组患者功能和总体健康维度评分均高于本组干预前,症状和特异性维度评分均低于本组干预前,且干预组患者功能和总体健康维度评分均高于对照组患者,症状和特异性维度评分均低于对照组患者,差异均有统计学意义(P<0.05)。两组患者KPS评分均低于本组干预前,且干预组患者KPS评分均低于对照组患者,差异均有统计学意义(P<0.05)。干预组患者皮肤黏膜损伤、肾脏毒性、神经毒性和过敏反应的发生率均低于对照组患者,差异均有统计学意义(P<0.05)。结论心理干预可减轻老年NSCLC化疗患者焦虑、抑郁的程度,提高其生活质量,对改善老年NSCLC化疗患者心理状态及生活质量有积极的影响。
Objective To analyze the effect of psychological intervention on the psychological status and quality of life(QOL)of elderly patients with non-small cell lung cancer(NSCLC).Method A total of 101 patients with NSCLC were included in the analysis and divided into intervention group(n=51)and control group(n=50)according to different intervention measures,respectively.The control group was given conventional chemotherapy in combination with life and general psychological guidance,while in the intervention group,psychological interventions were administered in addition to the regimens given for control group.Anxiety and depression were assessed before and after intervention by the self-rating anxiety scale(SAS)and self-rating depression scale(SDS),respectively.The European Organization for Research and Treatment of Cancer(EORTC)quality of life questionnaire-core 30(QLQ-C30)and Karnofsky performance status(KPS)scores were recorded to assess the QOL of both groups before and after interventions.Result After intervention,the SDS score of intervention group was lower than that before intervention,the SAS and SDS scores of control group were lower than that before intervention and intervention group(P<0.05).After the intervention,the scores of the patients in the two groups in terms of function and overall health were significantly improved,and scores of symptoms and specificity dimensions decreased significantly,furthermore,the intervention group had significantly higher scores of function and overall health and lower scores of symptoms and specificity compared to those in the control group,and the differences were of statistical significance(P<0.05).KPS score of the two groups decreased in both groups after interventions,with statistically lower KPS score recorded for intervention group versus control group(P<0.05).The incidence of skin and mucosal damage,nephrotoxicity,neurotoxicity and allergic reactions in the intervention group were lower than those in the control group,and the differences were statistically signific
作者
方云
王浩斌
朱利楠
FANG Yun;WANG Haobin;ZHU Linan(Department of Outpatient,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,He’nan,China)
出处
《癌症进展》
2020年第4期429-432,共4页
Oncology Progress
关键词
非小细胞肺癌
心理干预
生活质量
non-small cell lung cancer
psychological intervention
quality of life
