摘要
目的分析紫杉醇药物涂层球囊(DCB)症状性下肢动脉硬化闭塞症(ASO)的治疗效果.方法抽取2017年1月至2019年3月三门峡市中心医院收治的症状性下肢动脉硬化闭塞症患者60例为研究对象,所有患者均接受紫杉醇DCB治疗,对患者临床资料进行回顾性分析.结果所有患者均成功完成手术,成功率为100.00%,治疗后患者临床症状均得到显著改善,与术前相比ABI明显提高.对患者进行为期6个月的术后随访,发现ABI以及血管通畅率高于术前(P<0.05),其中7例患者发生靶病变再狭窄,但无需再次进行手术处理.无截肢、死亡等严重不良事件.结论对症状性动脉硬化闭塞症患者应用紫杉醇涂层球囊治疗,能有效预防再狭窄,提高保肢率,有助于改善患者预后,有临床推广应用价值.
Objective To analyze the therapeutic effects of paclitaxel drug-coated balloon(DCB)in symptomatic lower limb arteriosclerosis obliterana(ASO).Methods Sixty patients with admitted to Sanmenxia Central Hospital from January 2017 to March 2019 were selected as the research object,all patients were treated with paclitaxel DCB.and the clinical data of patients were retrospectively analyzed.Results All patients successfully completed the operation with success rate of 100.00%.After treatment,the clinical symptoms of the patients were significantly improved.Assessment stable angina scores of all patients were significantly improved after operation.The results showed that ABI and the patency rate of the vessel were significantly higher than that before operation(P<0.05).Among them,7 patients suffered from restenosis of target lesion,but no further surgical treatment was needed,and serious adverse events such as amputation and death hadn’t been be injured.Conclusions The application of paclitaxel-coated balloon in the treatment of ASO can effectively prevent restenosis,improve the limb rate,and help to improve the prognosis of patients.
作者
何锦来
毛天敏
严红军
胡永辉
He Jinlai;Mao Tianmin;Yan Hongjun;Hu Yonghui(Department of General Surgery,Sanmenxia Central Hospital,Sanmenxia 472000,China;Department of Vascular Surgery,Sanmenxia Central Hospital,Sanmenxia 472000,China)
出处
《中国实用医刊》
2019年第22期86-88,共3页
Chinese Journal of Practical Medicine
关键词
症状性下肢动脉硬化闭塞症
紫杉醇
球囊扩张成形
Symptomatic arteriosclerosis obliterans of lower extremities
Paclitaxel
Balloon dilatation
