摘要
目的回顾性总结超声引导下经皮射频消融治疗肝细胞癌肾上腺转移瘤的经验,评估其安全性及疗效。方法纳入2009年10月至2018年9月于中山大学附属第一医院行超声引导下肝细胞癌肾上腺转移瘤经皮射频消融治疗的患者16例,评估病灶的完全消融率及局部进展情况,总结肾上腺转移瘤消融相关的不良反应及并发症。结果16例患者的肾上腺转移瘤长径1.7~7.0(3.6±1.7)cm。中位消融时间为16 min,完全消融率为87.5%(14/16)。随访3~55个月,14例完全消融的患者中,3例出现肿瘤局部进展,肿瘤局部进展率21.4%(3/14)。不良反应及并发症方面,3例患者出现高血压危象(18.8%,3/16),2例患者术中出现心率减慢,其中1例合并频发室性早搏,暂停消融。全部病例无射频消融相关的死亡,无肾上腺功能衰竭症状体征出现。结论超声引导下经皮射频消融治疗肝细胞癌肾上腺转移瘤是一种安全、有效的治疗方式。
Objective To retrospectively summarize and evaluate the efficiency and safety of percutaneous ultrasound-guided radiofrequency ablation(RFA)for adrenal metastasis(AM)from hepatocellular carcinoma(HCC).Methods From October 2009 to September 2018,16 patients with AM from HCC who underwent percutaneous RFA in the First Affiliated Hospital of Sun Yat-Sen University were enrolled in the study.The complete ablation and local tumor progression rates were elevated,and the side effects and complications were summarized.Results The median ablation time of AM was 16 min.The complete ablation rate was 87.5%(14/16).After the follow-up period of 3 to 55 months,among the patients with complete ablation,there were 3 patients were detected local tumor progression(LTP),the LTP rate was 21.4%(3/14).As for the side effects and complications,3 patients were diagnosed as hypertension crisis(3/16,18.8%),2 showed reduced heart rate and 1 of them exhibited frequent premature ventricular contraction which resulted in termination of ablation.There was no ablation-related death or adrenal failure.Conclusions Percutaneous US-guided RFA is safe and effective in the treatment of AM originated from HCC.
作者
刘保娴
雷阳阳
谭洋
谢晓华
黄京智
谢晓燕
Liu Baoxian;Lei Yangyang;Tan Yang;Xie Xiaohua;Huang Jingzhi;Xie Xiaoyan(Department of Medical Ultrasound,the First Affiliated Hospital of Sun Yat-sen University,Guangzhou,510080,China)
出处
《中华超声影像学杂志》
CSCD
北大核心
2020年第2期149-152,共4页
Chinese Journal of Ultrasonography
基金
中山大学青年教师培育项目(18ykpy10)
广东省自然科学基金(2017A030310205)
国家自然科学基金(81701708,81530055)。
关键词
射频消融
肝细胞癌
肾上腺转移瘤
Radiofrequency ablation
Hepatocellular carcinoma
Adrenal metastasis
