摘要
目的:观察孟鲁司特钠治疗哮喘-慢阻肺重叠综合征的临床效果。方法:选取2016年1月-2018年9月就诊于笔者所在医院的哮喘-慢阻肺重叠综合征患者65例,将其随机分为试验组(33例)及对照组(32例)。对比两组患者治疗前后呼吸困难等级、生活质量积分及肺功能变化。结果:治疗前两组患者呼吸困难等级、生活质量及肺功能比较差异均无统计学意义(P>0.05);治疗后两组呼吸困难程度均较治疗前减轻,且试验组明显优于对照组,差异有统计学意义(P<0.05)。治疗后两组生活质量及肺功能均有改善,且试验组改善情况明显优于对照组,差异有统计学意义(P<0.05)。结论:在常规治疗基础上联合孟鲁司特钠治疗哮喘-慢阻肺重叠综合征能明显改善患者临床症状,提高生活质量,恢复其受损的肺功能。
Objective:To observe the clinical efficacy of Montelukast Sodium in the treatment of asthma-COPD overlap syndrome.Method:A total of 65 patients with asthma-COPD overlap syndrome treated in our hospital from January 2016 to September 2018 selected and were randomly divided into the experimental group(33 cases)and the control group(32 cases).The changes of dyspnea grade,quality of life score and pulmonary function before and after treatment were compared between the two groups.Result:There were no significant differences in dyspnea grade,quality of life and pulmonary function between the two groups before treatment(P>0.05).After treatment,the degree of dyspnea in both groups was reduced compared with that before treatment,and the experimental group was significantly better than the control group,the difference was statistically significant(P<0.05).The quality of life and pulmonary function were improved in both groups after treatment,and the improvement of the experimental group was significantly better than that of the control group,the differences were statistically significant(P<0.05).Conclusion:Combination of Montelukast Sodium and routine treatment can significantly improve the clinical symptoms of patients,improve the quality of life and restore the impaired pulmonary function of patients with asthma-COPD overlap syndrome.
作者
林诗烽
陈黎仙
林国勇
王智勇
LIN Shifeng;CHEN Lixian;LINGuoyong;WANG Zhiyong(Putian First Hospital,Putian 351100,China)
出处
《中外医学研究》
2020年第1期152-154,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
