摘要
目的:探究迁延性腹泻患儿应用布拉酵母菌与锌制剂治疗对临床治疗效果的影响.方法:将2017年7月-2019年7月笔者所在医院收治的62例迁延性腹泻患儿,随机分为两组,每组31例,对照组给予布拉酵母菌治疗,观察组给予布拉酵母菌与锌制剂联合治疗,对两组临床治疗效果、不良反应发生率及临床免疫指标进行对比.结果:观察组治疗总有效率为96.77%,高于对照组,差异有统计学意义(P<0.05);观察组不良反应发生率为6.45%,低于对照组,差异有统计学意义(P<0.05);观察组CD4+、CD4+/CD8+均高于对照组,CD8+低于对照组,差异均有统计学意义(P<0.05).结论:迁延性腹泻患儿应用布拉酵母菌与锌制剂联合治疗,能够有效提升临床治疗效果,降低不良反应发生率,改善临床指标.
Objective:To investigate the effect of Saccharomyces Boulardii and zinc preparation on the effect of clinical treatment in children with persistent diarrhea.Method:Sixty-two children with persistent diarrhea admitted to our hospital from July 2017 to July 2019 were randomly divided into two groups,31 patients in each group.The control group was treated with Saccharomyces Boulardii,and the observation group was given Saccharomyces Boulardii combined with zinc preparation,the clinical treatment efficiency,adverse reaction rate and clinical immune indicators were compared between the two groups.Result:The effective rate of observation group was 96.77%,which was significantly higher than that of the control group,the difference was statistically significant(P<0.05).The incidence of adverse reactions in the observation group was 6.45%,which significantly lower than that in the control group,the difference was statistically significant(P<0.05).The ratio of CD4+and CD4+/CD8+in the observation group was higher than that in the control group,while CD8+was lower than that in the control group,the differences were statistically significant(P<0.05).Conclusion:The combination of Saccharomyces Boulardii and zinc preparations in children with persistent diarrhea can effectively improve the clinical treatment effect,reduce the incidence of adverse reactions,and improve clinical indicators.
作者
赖丽芝
李薇
LAI Lizhi;LI Wei(Dongguan Binhaiwan Central of Hospital,Dongguan 523900,China)
出处
《中外医学研究》
2020年第2期19-20,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
基金
东莞市社会科技发展(一般)项目(项目编号：201950715025879)
关键词
布拉酵母菌
锌制剂
迁延性腹泻
临床疗效
Saccharomyces Boulardii
Zinc preparation
Persistent diarrhea
Clinical efficacy
