摘要
目的探讨肝动脉灌注化疗栓塞术(TACE)联合微波消融术(PMCT)治疗大肝癌的临床效果。方法选取郴州市第一人民医院南院2015年11月-2016年11月收治的大肝癌患者90例,根据不同手术方案分为对照组与联合组,各45例。对照组予以TACE治疗,联合组予以TACE联合PMCT治疗。比较两组临床效果,1年、2年生存率,治疗前后血清甲胎蛋白(AFP)水平,并观察两组并发症发生情况。结果联合组临床疗效优于对照组,1年、2年生存率高于对照组(P<0.05)。治疗前两组AFP水平比较,差异无统计学意义(P>0.05);治疗后联合组AFP水平低于对照组(P<0.05)。联合组并发症发生率低于对照组(P<0.05)。结论TACE联合PMCT治疗大肝癌的临床效果确切,可提高患者生存率,降低AFP水平,且安全性较高。
Objective To analyze the clinical effect of transcatheter arterial chemoembolization(TACE)combined with microwave ablation(PMCT)in the treatment of large liver cancer.Methods A total of 90 cases of patients with large liver cancer were selected from November 2015 to November 2016 in South Hospital of Chenzhou First People’s Hospital,which were divided into control group and combined group according to different operation plans,45 cases in each group.The control group was treated with TACE,and the combined group was treated with TACE and PMCT.The clinical effect,1-year and 2-year survival rates,serum AFP levels before and after treatment were compared between the two groups,and the incidence of complications were observed.Results The combined group of clinical effect was better than control group,and the 1-year and 2-year survival rates were higher than control group(P<0.05).Before treatment,There was no significant difference between the two groups(P>0.05);after treatment,the level of AFP of combined group was lower than control group(P<0.05).The incidence of complications of combined group was lower than control group(P<0.05).Conclusion TACE combined with PMCT have an exact clinical effect for large liver cancer,which can improve the survival rate of patients,effectively reduce the level of AFP,and has high safety.
作者
郭飞
GUO Fei(Department of Hepatobiliary Tumor Surgery,South Hospital of Chenzhou First Peoplef's Hospital,Chenzhou 423000,China)
出处
《临床合理用药杂志》
2019年第36期27-28,31,共3页
Chinese Journal of Clinical Rational Drug Use
关键词
大肝癌
肝动脉灌注化疗栓塞术
微波消融术
治疗结果
Large liver cancer
Transcatheter arterial chemoembolization
Microwave ablation
Treatment outcome
