摘要
目的通过分析4例肺原发结外NK/T细胞淋巴瘤(ENKTL)的CT表现,临床资料及病理特征,以提高对该病的认识。方法回顾性分析2012年1月至2018年9月在本院手术及穿刺活检病理证实的4例肺原发ENKTL胸部CT影像表现、临床资料和病理特征,并复习相关文献。结果3例肺原发ENKTL影像学表现为肿块型,1例表现为类肺炎型合并肿块型。4例患者共4个肿块,病变内出现坏死和"血管造影征"各6个,空气支气管征2个,3个肿块合并周围片絮状高密度影,2例患者出现肺裂局限征。3例患者合并单侧或双侧胸腔积液,2例胸膜或叶间裂胸膜增厚,1例伴发患侧纵隔淋巴结肿大。结论肺原发ENKTL影像学上可出现肿块、实变、结节等征象,肿块内出现坏死及"血管造影征"为常见特征,也可出现病灶周围片絮状高密度影、空气支气管征、胸腔积液、胸膜增厚等肺内外表现,但这些征象的特异性并不高,影像上不易与肺部感染、周围型肺癌等疾病鉴别,临床确诊仍依赖于病理及免疫组织化学结果。
Objective Primary pulmonary extranodal NK/T-cell lymphoma(ENKTL)is extremely rare.The aim of this study was to improve the understanding of CT findings in primary pulmonary ENKTL.Methods The CT findings,clinical data and pathological features of 4 cases of primary pulmonary ENKTL confirmed by surgery and biopsy in our hospital from January 2012 to September 2018were retrospectively analyzed,and relevant literature were reviewed.Results Three cases of primary pulmonary ENKTL showed a mass-like appearance,one case showed a pneumonia-like complicated with mass.Four patients had a total of 6 masses.Necrosis and angiography occurred in all the masses.There were 2 with air bron-chograms,3 with lumps with high-density shadows around the mass,and 2 patients with fissure limitation sign.Three pa-tients had unilateral or bilateral pleural effusions,two had pleural or interlobular pleural thickening,and one had associated mediastinal lymphadenopathy.Conclusion The images of primary pulmonary ENKTL were varied.Necrosis and angiogra-phy in the mass were common features,Other signs like air bronchograms,fissure limitation sign,pleural effusion and pleu-ral thickening can also be seen in patients with primary pulmonary ENKTL.Therefore,the image is not easy to differentiate from other diseases such as lung infection andperipheral lung cancer.The final diagnosis is still dependent on pathological and immunohistochemical results.
作者
王小丽
楼海燕
陈峰
WANG Xiaoli;LOU Haiyan;CHEN Feng(The First Afflilated Hospital,Zhejiang University,Hanzhou 310000,P.R.China)
出处
《临床放射学杂志》
CSCD
北大核心
2019年第12期2446-2449,共4页
Journal of Clinical Radiology
