摘要
目的提升对获得性免疫缺陷综合征(AIDS)合并中枢神经系统新型隐球菌及结核分枝杆菌混合感染的认知。方法分析1例AIDS合并新型隐球菌性脑膜炎及结核性脑膜炎患者的诊疗过程,并结合相关文献进行复习。结果1例38岁男性患者因AIDS合并新型隐球菌性脑膜炎于2015年3月17日于武汉大学中南医院住院诊治,完善检查后确诊为新型隐球菌及结核分枝杆菌颅内混合感染,给予抗感染及对症综合治疗后,病情缓解,预后较好。结论AIDS合并隐球菌性脑膜炎及结核性脑膜炎患者应及时诊断,予以抗隐球菌、抗结核综合治疗并适时启动抗逆转录病毒治疗,可改善预后。
Objective To improve the understanding of acquired immunodeficiency syndrome(AIDS)and central nervous system(CNS)combined infection of Cryptococcus neoformans and Mycobacterium tuberculosis.Methods The diagnosis and treatment of a case of AIDS combined with new cryptococcal meningitis and tuberculous meningitis were analyzed,and relevant literatures were reviewed.Results On March 17th,2015,a 38-year-old male patient with AIDS complicated with cryptococcal meningitis was admitted to Zhongnan Hospital of Wuhan University.After complete examination,the case was diagnosed as mixed infection of Cryptococcus neoformans and Mycobacterium tuberculosis.After antiinfection and comprehensive symptomatic treatment,the condition of the case was relieved and the prognosis was relatively well.Conclusions For patients with AIDS combined with cryptococcal meningitis and tuberculous meningitis,timely diagnosis,combined treatment with anti-cryptococcus and anti-tuberculosis and initiation of antiretroviral therapy at the right moment are expected to improve the prognosis.
作者
胡荣华
邓莉萍
陈铁龙
熊勇
Hu Ronghua;Deng Liping;Chen Tielong;Xiong Yong(Department of Infectious Diseases,Zhongnan Hospital of Wuhan University,Wuhan 430071,China)
出处
《中华实验和临床感染病杂志（电子版）》
CAS
2019年第6期506-511,共6页
Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition)
基金
“十三五”艾滋病和病毒性肝炎等重大传染病防治科技重大专项(No.2017ZX10202101-001)
