摘要
目的研究关节镜部分切除术(APR)治疗膝关节半月板损伤(IMK)的临床疗效。方法选择该院2015年1月至2018年12月收治的IMK患者96例作为研究对象,按照随机数字表法分为APR组(n=48)、非手术组(n=48)。APR组行APR治疗,非手术组行关节腔灌注治疗。观察两组治疗前、治疗6个月后骨关节炎指数(WOMAC)、国际膝关节评分委员会(IKDC)评分及膝关节活动度,疼痛程度,血清5-羟色胺(5-HT)、P物质(SP)、去甲肾上腺素(NE)等疼痛因子水平。结果治疗后6个月,APR组WOMAC指数小于非手术组,IKDC评分及膝关节活动度均大于非手术组,差异均有统计学意义(P<0.05);APR组疼痛程度及血清5-HT、SP、NE水平均低于非手术组,差异均有统计学意义(P<0.05);APR组优良率(93.75%)高于非手术组(72.92%),差异有统计学意义(P<0.05)。结论APR治疗IMK有助于改善患者症状,提高膝关节活动度,减少生成疼痛因子,缓解患者疼痛,疗效确切。
Objective To study the clinical effect of arthroscopic partial resection(APR)for treating injury of meniscus knee(IMK).Methods Ninety-six patients with IMK admitted and treated in this hospital from January 2015 to December 2018 were selected as the study subjects and divided into the APR group(n=48)and non-surgery group(n=48)according to the random number table method.The APR group conducted the APR treatment,and non-surgery group received the articular cavity perfusion treatment.The WOMAC osteoarthritis index,IKDC score,knee mobility,pain degree,pain factors levels of serum serotonin(5-HT),substance P(SP)and norepinephrine(NE)before treatment and in 6 months after treatment were observed in the two groups.Results In 6 months after surgery,the WOMAC index in the APR group was smaller than that in the non-surgery group,and the IKDC score and knee joint mobility were greater than those in the non-surgery group(P<0.05).The pain degree and serum 5-HT,SP and NE levels in the APR group were lower than those in the non-surgery group,and the differences were statistically significant(P<0.05).The excellent and good rate of the APR group was higher than that of the non-surgery group,and the difference was statistically significant(93.75% vs.72.92%,P<0.05).Conclusion APR in treating IMK is helpful to improve the patient's symptoms,increase the motion degree of knee joint,reduce the formation of pain factors,and relieve the patient's pain with definite curative effects.
作者
杨飞
刘妍科
吴金钏
李建平
胡杰斯
YANG Fei;LIU Yanke;WU Jinchuan;LI Jianping;HU Jiesi(Department of Joint Surgery,Shizhong District Hospital of Traditional Chinese Medicine,Leshan,Sichuan 614000,China)
出处
《现代医药卫生》
2020年第5期672-674,678,共4页
Journal of Modern Medicine & Health
