摘要
帕金森病(Parkinson’s disease,PD)是一种常见于中老年人缓慢进展的神经系统变性疾病,临床表现主要包括静止性震颤、运动迟缓、肌强直和姿势步态异常等运动障碍,同时伴有一些非运动症状,显著降低了患者的生活质量,给家庭及社会带来了极大的负担。随着医学的发展,人们对帕金森病的发病机制逐渐认识,其治疗方法层出不穷,但目前国内外PD的治疗仍以药物为主。就国内外帕金森病常见的药物治疗的最新进展进行综述,以期为广大临床医生在帕金森病药物治疗方面提供一些帮助。
Parkinson’s disease(PD) is a slow-developing central nervous system degenerative disease common in middle-aged and elderly people. It mainly causes dyskinesia such as resting tremor, muscle rigidity, bradykinesia and abnormal posture gait. There are some non-motor symptoms that significantly reduce the quality of life of patients and bring a great burden on families and society. With the development of medicine, people gradually understand the pathogenesis of Parkinson’s disease, and its treatment methods are endless, but at present, the treatment of PD at home and abroad is still based on drugs. This article reviews the recent advances in drug therapy for Parkinson’s disease at home and abroad, with a view to providing some clinicians with some help in the treatment of Parkinson’s disease.
作者
苏红军
SU Hongjun(Department of Neurology,Baodi District People's Hospital,Tianjin 301800,China)
出处
《继续医学教育》
2020年第2期148-151,共4页
Continuing Medical Education
关键词
帕金森病
震颤
多巴胺
药物治疗
单胺氧化酶抑制
研究进展
Parkinson’s disease
tremor
dopamine
drug therapy
monoamine oxidase inhibition
research progress
