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经直肠超声联合前列腺特异抗原密度诊断前列腺癌的临床应用价值研究 被引量:13

Clinical Value of Transrectal Ultrasound Combined with Prostate Specific Antigen Density in the Diagnosis of Prostate Cancer
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摘要 为探讨经直肠超声与前列腺特异抗原密度(PSAD)联合检查诊断前列腺癌的临床应用价值,选取本院2013年9月~2018年9月期间内接收的97例血清前列腺特异性抗原(PSA)患者实施研究。所有患者均行经直肠超声与前列腺特异抗原密度(PSAD)联合检查,并与手术病理结果进行对比。观察PSAD检查结果,分析经直肠超声与PSAD联合检查的诊断符合率,并对比病理结果与经直肠超声和PSAD联合检查的准确率、灵敏性、特异性情况,分析前列腺癌患者经直肠超声检查的影像学特征及内部回声情况。与病理结果对比,经直肠超声与PSAD联合检查对前列腺癌、移行细胞癌、黏液腺癌检出率均稍低(P>0.05);经直肠超声与PSAD联合检查的准确率、灵敏性、特异性较病理检查均稍低(P>0.05)。经直肠超声检查后根据图像表现可将疾病分为弥漫性、结节型、无结节型3型,不同类型的影像学特征及内部回声情况表现不同,表明经直肠超声与PSAD联合诊断前列腺癌准确性较高,并且可清晰地对不同疾病类型的内部回声作出反映,临床实用价值较高,值得加以推广。 To investigate the clinical value of transrectal ultrasound combined with prostate specific antigen density(PSAD)in the diagnosis of prostate cancer,97 patients with elevated PSA from September 2013 to September 2018 were enrolled in the study.All patients were examined by transrectal ultrasound and PSAD,compared with the pathological results.The PSAD inspection results were observed,and the diagnosis coincidence rate of transrectal ultrasound+PSAD and the pathological examination was analyzed.Then the accuracy,sensitivity and specificity of the the transrectal ultrasonography combined with PSAD were compared with those of pathological examination.Finally,the imaging features and internal echo of transrectal ultrasonography in patients with prostate cancer were analyzed.The detection rate of prostate cancer,transitional cell carcinoma and mucinous adenocarcinoma by transrectal ultrasound and PSAD was slightly lower than pathological examination(P>0.05).The accuracy,sensitivity and specificity of transrectal ultrasound combined with PSAD were slightly lower than those of pathological examination(P>0.05).According to the ultrasound image,the cancer can be divided into three types:diffuse,nodular and no nodular.The imaging characteristics and internal echo of different types are different.It is indicated that the accuracy of transrectal ultrasound combined with PSAD in the diagnosis of prostate cancer is high,which can clearly reflect the internal echo of different disease types.It is worth popularizing because of its high clinical practical value.
作者 冯亮 师琳 蒋益民 FENG Liang;SHI Lin;JIANG Yimin(Department of Acoustic Medicine,Shanghai Sixth People’s Hospital East Campus,Shanghai University of Health and Medicine,Shanghai 201306,P.R.China)
出处 《影像科学与光化学》 CAS 2020年第2期323-327,共5页 Imaging Science and Photochemistry
基金 上海健康医学院百人师资人才库(2017039)资助
关键词 经直肠超声 前列腺特异抗原密度 前列腺癌 病灶检出率 影像学特征 内部回声 transrectal ultrasound PSAD prostate cancer detection rate of lesions imaging characteristics internal echo
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