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间皮瘤误诊为结核1例及文献复习

Mesothelioma misdiagnosed as tuberculosis:1 case report and literature review
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摘要 目的探讨恶性腹膜间皮瘤的诊断及治疗策略。方法介绍1例腹膜间皮瘤的诊治经过,总结目前恶性腹膜皮瘤的诊断及治疗进展。结果患者被误诊为结核,后经腹腔镜活检得到确诊。术后病理示:免疫组织化学染色CK(+)、阳性对照(+),CR(+),D2-40(+)、阳性对照(+),CK5/6(+)、阳性对照(+),CK7散在(+)、阳性对照(+),Ki67阳性细胞数15%、阳性对照(+),WT1(+)、阳性对照(+),P53灶性(+)、阳性对照(+),P63(-)、阳性对照(+),CK20(-)、阳性对照(+),CDX-2(-)、阳性对照(+)。结论恶性腹膜间皮瘤诊断中一定要注意与腹腔结核鉴别,目前首选的治疗方法仍然是细胞还原手术联合腹腔热化疗。 Objective To investigate the diagnosis and treatment of malignant peritoneal mesothelioma.Methods To recommend the diagnosis and treatment of 1 case of malignant peritoneal mesothelioma,than summarize the diagnosis and treatment of malignant peritoneal mesothelioma.Results The patient was misdiagnosed as tuberculosis and confirmed by laparoscopic biopsy later.Postoperative pathology:immunohistochemical staining CK(+),positive control(+),CR(+),D2-40(+),positive control(+),CK5/6(+),positive control(+),CK7 scattered(+),positive control(+),Ki67 positive cells 15%,positive control(+),WT1(+),positive control(+),P53 focal(+),positive control(+),P63(-),positive control(+),CK20(-),positive control(+),CDX-2(-),positive control(+).Conclusion The diagnosis of malignant peritoneal mesothelioma must be differentiated from abdominal tuberculosis.The current preferred treatment is still cell reduction surgery combined with intraperitoneal thermochemotherapy.
作者 孙伟 毛青 SUN Wei;MAO Qing(Department of Infectious Disease,the First Affiliated Hospital of Army Medical University,400038,China)
出处 《重庆医学》 CAS 2020年第4期573-576,共4页 Chongqing medicine
关键词 间皮瘤 腹膜 结核 误诊 mesothelioma peritoneum tuberculosis diagnostic errors
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