摘要
冠状动脉粥样硬化性心脏病(冠心病)经皮冠状动脉介入(PCI)术后患者出现焦虑抑郁的比例较高。焦虑抑郁状态是冠心病PCI术后患者再发主要心血管不良事件的独立预测因子,且抑郁情绪使冠心病PCI术后患者死亡率明显增高。PCI术后患者发生焦虑抑郁的机制主要与大脑"边缘系统-纹状体-丘脑"神经递质环路被阻断有关,其危险因素主要是性别、年龄、受教育程度、家庭经济条件等基本因素和冠状动脉病变严重程度以及D型人格,治疗上为心理干预、护理干预和中西医药物治疗。
There is a high incidence of anxiety and depression among patients after percutaneous coronary intervention( PCI). Anxiety and depression are independent predictors of major adverse cardiovascular events and death following PCI. The pathogenesis of anxiety and depression in post-PCI patients is mainly associated with the interception of neurotransmitters in brain’ s limbic system-striatum-thalamic loop. Risk factors of post-PCI anxiety and depression are gender,age,education,financial status,as well as the severity of coronary lesion and type D personality,etc. Major treatments include psychological intervention,nursing care,traditional Chinese medicine and western medicine.
作者
王思璇
杨宇彤
高阳
马涵英
Wang Sixuan;Yang Yutong;Gao Yang;Ma Hanying(the Sixth Clinical Medical School,Capital Medical University,Beijing 100069,China;Department of General Medical Practice,Beijing Anzhen Hospital,Capital Medical University,Beijing 100029,China)
出处
《中国医药》
2020年第1期135-139,共5页
China Medicine
关键词
经皮冠状动脉介入
焦虑
抑郁
Percutaneous coronary intervention
Anxiety
Depression
