摘要
目的探讨克林霉素联合电子支气管镜冲洗治疗急性肺脓肿的疗效和安全性。方法选择2016年6月至2018年6月本院收治的急性肺脓肿患者92例作为研究对象,随机数表法分为观察组和对照组,各46例,对照组接受克林霉素常规治疗,观察组在此基础上给予电子支气管镜冲洗治疗。比较两组患者治疗后的疗效和并发症发生情况,治疗前后肺功能及血气指标变化情况。结果治疗后,观察组总有效率为97.83%,高于对照组的78.26%(P<0.05);两组患者FEV1、PaO2、PaO2/FiO2、SpO2水平均升高,观察组高于对照组(P<0.05);观察组并发症发生率为4.35%,低于对照组的17.39%(P<0.05)。结论在常规治疗基础上给予电子支气管镜冲洗治疗急性肺脓肿患者疗效确切,可有效改善患者的肺功能,降低并发症率,安全可行。
Objective To investigate the efficacy and safety of clindamycin combined with electronic bronchoscopy in the treatment of acute lung abscess.Methods A total of 92 patients with acute lung abscess admitted to our hospital from June 2016 to June 2018 were enrolled.The random number table method was divided into observation group and control group,with 46 cases in each group,and the control group received routine treatment with clindamycin.The observation group was given an electron bronchoscope irrigation treatment on this basis.The efficacy and complications of the two groups of patients after treatment,the changes of lung function and blood gas index before and after treatment were compared.Results After treatment,the total effective rate of the observation group was 97.83%,which was higher than that of the control group(78.26%)(P<0.05).The levels of FEV1,PaO2,PaO2/FiO2,and SpO2 increased in the two groups,and the observation group was higher than the control group group(P<0.05);the incidence of complications in the observation group was 4.35%,which was lower than 17.39%in the control group(P<0.05).Conclusion On the basis of conventional treatment,the treatment of patients with acute lung abscess treated with electronic bronchoscopy is effective,which can effectively improve the lung function of patients and reduce the complication rate,which is safe and feasible.
作者
怀宝刚
Huai Baogang(Department of Pulmonary Disease,Pingyi Hospital of Traditional Chinese Medicine,Pingyi,Shandong,273300,China)
出处
《当代医学》
2020年第6期45-47,共3页
Contemporary Medicine
关键词
克林霉素
电子支气管镜
急性肺脓肿
肺功能
并发症
Clindamycin
Electronic bronchoscope
Acute pulmonary abscess
Pulmonary function
Complication
