摘要
目的分析糖尿病足患者血流变与黏附因子变化及意义。方法择2018年2月-2019年2月来该院诊疗的145例糖尿病足患者为分析对象,将其依据Wagner分级分为3组,研究1组(n=46)、研究2组(n=52)及研究3组(n=47),而后对两组患者均行血流变及相关黏附因子检测,对比两组患者的相关检测结果。结果3组患者高切粘度、低切粘度、血小板聚焦指数及血浆比粘度大小排序均为:研究3组﹥研究2组﹥研究1组,且3组的四类血流变相关指标差异有统计学意义(P﹤0.05);三组患者ICAM-1及VCAM-1水平高低排序均为:研究3组﹥研究2组﹥研究1组,且3组患者的两类黏性因子水平差异有统计学意义(P﹤0.05)。结论血流变与黏附因子变化对糖尿病足患者意义十足,可有效性反映糖尿病足患者的相关体征情况。
Objective To analyze the changes and significance of blood rheology and adhesion factors in diabetic foot patients.Methods A total of 145 patients with diabetic foot who were selected for treatment in our hospital from February 2018 to February 2019 were included in the study.They were divided into three groups according to Wagner classification.Study group 1(n=46),study 2 group(n=52),and study group 3(n=47),then both groups of patients were tested for hemorheology and related adhesion factors,and the results of the two groups were compared.Results The high-viscosity,low-cut viscosity,platelet focus index and plasma specific viscosity were ranked in the three groups:study group3>study 2 group>study group 1,and the four groups of four types of blood rheology related indicators were significantly different(P<0.05);the levels of ICAM-1 and VCAM-1 in the three groups were:study group 3>study 2 group>study group 1,and the levels of the two types of adhesion factors were significantly different in the three groups(P<0.05).Conclusion Changes in blood rheology and adhesion factors are of great significance for diabetic foot patients,and can be effective in reflecting the relevant signs of diabetic foot patients.
作者
林云霞
LIN Yunxia(Shandong Shan County Center for Disease Control and Prevention,Heze Shandong,274300,China)
出处
《双足与保健》
2019年第23期90-91,共2页
Biped and Health
关键词
糖尿病足
血流变
黏附因子
Diabetic foot
Blood rheology
Adhesion factor
