摘要
目的探讨血清鳞状细胞癌抗原(SCC)、糖类抗原19-9(CA19-9)、癌胚抗原(CEA)检查对诊断食管癌的临床价值分析。方法选取2016年5月至2018年5月我院收治的420例食管癌患者为研究对象,纳入食管癌组,另选同期健康体检者60例纳入对照组,检测三组SCC、CA19-9、CEA水平及阳性检测率,探讨以上指标在诊断食管癌中的价值。结果食管癌组患者血清SCC、CA19-9、CEA水平均显著高于对照组,差异有统计学意义(P<0.05);SCC、CA19-9、CEA三种指标联合检测阳性率76.90%显著高于单项检测30.95%、40.00%、25.95%,差异有统计学意义(P<0.05);血清SCC、CA19-9、CEA水平随着食管癌患者分期的递增,呈现上升趋势,差异有统计学意义(P<0.05)。结论SCC、CA19-9、CEA三项指标联合诊断食管癌阳性率显著高于单项检测,还可反映疾病的进展,为临床治疗提供可靠依据。
Objective To explore the clinical value of serum squamous cell carcinoma antigen(SCC),carbohydrate antigen 19-9(CA19-9)and carcinoembryonic antigen(CEA)in the diagnosis of esophageal cancer.Methods A total of 420 patients with esophageal cancer admitted to our hospital from May 2016 to May 2018 were selected for the study and enrolled in esophageal cancer group.Another 60 healthy examiners were enrolled in control group,and the levels and positive detection rates of SCC,CA19-9 and CEA were detected,and the value of the above indicators in the diagnosis of esophageal cancer was explored.Results The serum levels of SCC,CA19-9 and CEA in esophageal cancer group were significantly higher than those in control group(P<0.05).The positive rate of combined detection of SCC,CA19-9 and CEA was 76.90%,which was significantly higher than that of single detection with 30.95%,40.00%and 25.95%(P<0.05).The serum levels of SCC,CA19-9and CEA were increased with the increase of staging of patients with esophageal cancer(P<0.05).Conclusion The positive rate of combined detection of SCC,CA19-9 and CEA is significantly higher than that of single detection in the diagnosis of esophageal cancer.And it can also reflect the progress of disease and provide a reliable basis for clinical treatment.
作者
王雨梦
WANG Yu-meng(Department of Medical Laboratory,Zhumadian Central Hospital,Zhumadian 463000,Henan Province,China)
出处
《罕少疾病杂志》
2019年第6期55-57,共3页
Journal of Rare and Uncommon Diseases
