摘要
[目的]应用"三步法"治疗幽门螺杆菌(Hp)感染感染临床疗效观察。[方法]按随机数字表法将300例Hp感染患者随机分为治疗组(三步法+四联方案)150例和对照组(四联方案)150例,治疗后分别观察2组患者临床疗效、主要不良反应、1年后Hp复感率。[结果]治疗组Hp根除率高于对照组(96.67%:85.33%,P<0.05)。治疗组根治Hp过程中主要不良反应明显少于对照组(P<0.05)。治疗1年后随访,治疗组Hp复感率(14.28%)低于对照组(24.26%)(P<0.05)。[结论]"三步法"治疗Hp感染疗效确切,依从性高,不良反应较少,Hp难治性及易复发可能与"湿"邪有关。
[Objective]To observe the clinical efficacy of "three-step" therapy on Helicobacter pylori infection.[Methods]300 cases of Helicobacter pylori patients were randomly divided into treatment group(three-step combined four-link scheme) and control group(four-link scheme),150 cases in each group. The clinical efficacy, main adverse reactions and the rate of Helicobacter pylori relapse after one year of treatment were observed in each group. [Results]The eradication rate of Helicobacter pylori in treatment group was higher than that in control group(96.67% vs. 85.33%, P<0.05). The main adverse reactions in the treatment group were significantly less than those in the control group(P<0.05). Follow-up conducted after one year of treatment showed that the relapse rate of Helicobacter pylori in the treatment group was lower than that in the control group(14.28% vs. 24.26%, P<0.05).[Conclusion]Three-step therapy is effective in the treatment of Helicobacter pylori infection, which has high compliance and low side effects. The refractory and easy recurrence of Helicobacter pylori may be related to the pathogen of dampness.
作者
邱伟
杨振斌
夏文娟
方晓华
殷鸿
陈莉丽
QIU Wei;YANG Zhen-bin;XIA Wen-juan;FANG Xiao-hua;YIN Hong;CHEN Li-li(Department of Spleen and Stomach,Yangzhou Hospital of Traditional Chinese Medicine of Jiangsu Province,Yangzhou 225000,China)
出处
《中国中西医结合消化杂志》
CAS
2020年第1期20-22,共3页
Chinese Journal of Integrated Traditional and Western Medicine on Digestion
关键词
幽门螺杆菌感染
治湿五法
四联根治幽门螺杆菌方案
helicobacter pylori infection
five methods for dampness control
quadruple therapy for helicobacter pylori
