摘要
目的:调查慢性阻塞性肺疾病(COPD)患者合并焦虑、抑郁的发生率,并探讨有效治疗COPD合并焦虑、抑郁患者的方案。方法:选择2018年1月-2019年1月在本院治疗的300例COPD患者,根据医院焦虑抑郁量表(HAD)评分统计COPD患者伴焦虑、抑郁的发生率;将COPD伴焦虑、抑郁患者按随机数字表法分为对照组和观察组。对照组采用COPD规范化治疗联合认知行为干预,观察组在对照组基础上给予草酸艾司西酞普兰治疗,比较两组治疗前后的HAD评分、肺功能、生活质量、呼吸困难评分及6分钟步行试验(6MWD)情况。结果:300例COPD患者中伴焦虑、抑郁60例,发病率为20.00%。治疗后,两组焦虑与抑郁评分均明显低于治疗前,且观察组均低于对照组(P<0.05);治疗后,两组FEV1与FEV1/FVC%均高于治疗前,且观察组均高于对照组(P<0.05)。治疗后,两组各项生活质量评分及总分均低于治疗前,且观察组均低于对照组(P<0.05)。治疗后,观察组呼吸困难评分低于治疗前及对照组,且观察组6MWD情况优于治疗前与对照组(P<0.05)。结论:COPD患者伴焦虑抑郁发生率较高,在COPD规范化治疗基础上应用草酸艾司西酞普兰联合认知行为干预能够有效改善COPD伴焦虑、抑郁患者的精神状态,有效改善患者的肺功能及生活质量,减轻呼吸困难程度,增强患者的运动能力。
Objective: To investigate the incidence of anxiety and depression in patients with chronic obstructive pulmonary disease(COPD), and to explore the effective treatment of COPD patients with anxiety and depression. Method: A total of 300 COPD patients treated in our hospital from January 2018 to January 2019 were selected, and the incidence of COPD patients with anxiety and depression was calculated according to the hospital anxiety and depression scale(HAD) score. COPD patients with anxiety and depression were divided into control group and observation group according to the random number table method. The control group was treated with standardized treatment of COPD combined with cognitive behavioral intervention, and the observation group was treated with Escitalopram Oxalate on the basis of the control group. The HAD score, lung function, quality of life, dyspnea score and 6-minute walking experiment(6 MWD) before and after treatment were compared between the two groups. Result: Among the 300 COPD patients, 60 cases were accompanied by anxiety and depression, the incidence of COPD patients with anxiety and depression was 20.00%. After treatment, anxiety and depression scores in both groups were significantly lower than those before treatment, and those in the observation group were lower than those in the control group(P<0.05). After treatment, FEV1 and FEV1/FVC% in both groups were higher than those before treatment, and those in the observation group were higher than those in the control group(P<0.05). After treatment, the all scores and total scores of quality of life in the two groups were lower than those before treatment, and those in the observation group were lower than those in the control group(P<0.05). After treatment, the score of dyspnea in the observation group was lower than those before treatment and the control group, and the condition of 6 MWD in the observation group was better than those before treatment and the control group(P<0.05). Conclusion: The incidence of COPD patients with anxiety a
作者
黄健
胡晨
程吕欢
HUANG Jian;HU Chen;CHENG Luhuan(Jiangxi Chest Hospital,Nanchang 330006,China)
出处
《中国医学创新》
CAS
2019年第35期160-164,共5页
Medical Innovation of China
基金
江西省卫生计生委科技计划项目(20185470)
关键词
慢性阻塞性肺疾病
焦虑
抑郁
草酸艾司西酞普兰
Chronic obstructive pulmonary disease
Anxiety
Depression
Escitalopram Oxalate
