摘要
目的探究经鼻肠管肠内营养对重型颅脑损伤(sTBI)患者营养状况的改善情况。方法选取2015年1月至2018年12月本院收治的sTBI患者246例,随机数字法分为两组,各123例。观察组采用鼻肠管营养支持,对照组选择鼻胃管营养支持。分别在治疗前、治疗7 d、14 d后,检测两组患者营养相关血液学指标、GCS评分并记录治疗14 d过程中两组患者鼻饲管相关并发症发生情况。结果治疗7 d、14 d后,两组患者Hb、ALB、PA水平均高于治疗前,其中观察组Hb、ALB、PA显著高于对照组,差异均有统计学意义(均P<0.05);治疗14 d过程中,观察组肺部感染、消化道出血、反流性食管炎、电解质紊乱发生率分别为10.57%、16.26%、4.88%、13.01%,均低于对照组51.21%、30.08%、29.27%、37.40%,差异均有统计学意义(均P<0.05);治疗7 d、14 d后,观察组GCS评分分别为(9.1±2.3)分、(11.6±1.3)分,均高于对照组(7.9±2.9)分、(10.3±1.9)分,差异均有统计学意义(均P<0.05);结论对于sTBI患者进行肠内营养支持选择鼻肠管营养支持能够有效改善患者的营养状况,并且并发症发生情况也较低,具有更好的安全性。
Objective To investigate the improvement of nutritional status of patients with severe craniocerebral injury(sTBI)by enteral nutrition through nasointestinal tube.Methods A total of 246 patients with sTBI admitted to our hospital from January 2015 to December 2018 were randomly divided into observation group and control group,123 cases in each group.The observation group received nutrition support through nasointestinal tube,and the control group received nutrition support through nasogastric tube.The nutritionrelated hematological parameters and GCS scores of the two groups were measured before treatment,7 days after treatment,and 14 days after treatment,and the complications of nasal feeding tube in the two groups were recorded.Results At 7 days after treatment and 14 days after treatment,the levels of Hb,ALB,and PA in the two groups were higher than those before treatment,the levels of Hb,ALB,and PA in the observation group were significantly higher than those in the control group(P<0.05).During the course of treatment for 14 days,the incidence of lung infection,gastrointestinal bleeding,reflux esophagitis,electrolyte disturbance in the observation group were 10.57%,16.26%,4.88%,13.01%,which were significantly lower than those in the control group(51.21%,30.08%,29.27%,37.40%)(P<0.05).After 7,14 days of treatment,the GCS score of the observation group was significantly higher than that of the control group[(9.1±2.3)vs.(7.9±2.9),(11.6±1.3)vs.(10.3±1.9)](P<0.05).Conclusion Enteral nutrition support through nasointestinal tube can improve the nutritional status of sTBI patients,with lower incidence of complications and better safety.
作者
刘琳琳
任云云
Liu Linlin;Ren Yunyun(Department of Neurology,Liaocheng Third People's Hospital,Liaocheng 252000,China)
出处
《国际医药卫生导报》
2020年第1期120-123,共4页
International Medicine and Health Guidance News
关键词
鼻肠管喂养
肠内营养支持
重型颅脑损伤
营养状况
Nasointestinal tube feeding
Enteral nutrition support
Severe craniocerebral injury
Nutritional status