摘要
目的探究清胃散联合头孢拉定治疗牙周炎的临床疗效。方法将本院2018年6月~2019年1月间50例牙周炎患者作为研究对象,随机分为实验组(26例)与对照组(24例),两组均先给予常规治疗,对照组同时给予清胃散治疗,实验组在对照组基础上采用头孢拉定治疗,观察两组治疗前后菌斑指数、龈沟出血指数、牙周袋探针深度变化及治疗效果与不良反应情况。结果两组治疗前,菌斑指数、牙周袋探针深度、龈沟出血指数比较,差异无统计学意义(P>0.05);治疗后,两组菌斑指数、牙周袋探针深度、龈沟出血指数均降低,实验组降低比对照组更明显,差异有统计学意义(P<0.05);经清胃散联合头孢拉定治疗后的实验组,治疗总有效率为96.2%,对照组为70.8%,差异有统计学意义(P<0.05);两组均未见严重不良反应,仅实验组1例(3.8%)轻微腹泻,对照组未发生不良反应,差异无统计学意义(P>0.05)。结论清胃散联合头孢拉定治疗牙周炎可有效改善临床症状,效果显著,副作用少,值得采用。
Objective To explore the clinical curative effects of Qingwei powder combined with cefradine in treatment of periodontitis.Methods 50 patients with periodontitis in our hospital from June 2018 and January 2019 were selected as research objects.They were randomly divided into the experimental group(26 cases)and the control group(24 cases).Both groups were given conventional treatment.The control group was treated with Qingwei powder at the same time while the experimental group was treated with cefradine on the basis of the control group.The plaque index,sulcus bleeding index,periodontal pocket probe depth change,curative effects and adverse reactions were observed before and after treatment.Results Before treatment,there was no statistically significant difference in plaque index,periodontal pocket probe depth and sulcus bleeding index between the two groups(P>0.05).After treatment,the plaque index,periodontal pocket probe depth and sulcus bleeding index were decreased,and the decrease of the experimental group was more obvious than that of the control group.The difference between the two groups was statistically significant(P<0.05).In the experimental group treated by Qingwei powder combined with cefradine,the total effective rate was 96.2%.The total effective rate of the control group was 70.8%.The difference was statistically significant(P<0.05).No serious adverse reactions were observed in either group.Only 1 patient(3.8%)in the experimental group had mild diarrhea,and no adverse reactions occurred in the control group.The difference was not statistically significant(P>0.05).Conclusion Qingwei powder combined with cefradine in treatment of periodontitis can effectively improve clinical symptoms,with significant curative effects and fewer side effects,which is worthy of adoption.
作者
陈园园
曾柳
CHEN Yuanyuan;ZENG Liu(Yangchun People’s Hospital,Guandong,Yangchun 529600,China)
出处
《中国医药科学》
2020年第1期125-127,共3页
China Medicine And Pharmacy
关键词
清胃散
头孢拉定
牙周炎
菌斑指数
Qingwei powder
Cefradine
Periodontitis
Plaque index
