摘要
目的探讨不同剂量达克罗宁对患者胃镜检查效果的临床影响。方法将2018年10月~2019年4月来我院接受胃镜检查的1480例患者作为研究对象,采用随机数字表法分为对照组(达克罗宁剂量:8mL)和观察组(达克罗宁剂量:10mL),每组740例,对每位患者行胃镜检查前30分钟内口服达克罗宁药物,按照以上比例。对比不同剂量达克罗宁药物与黏膜可视度的相关性、胃镜检查时间、操作满意度、胃镜检查下患者上消化道病变检出情况等。结果达克罗宁10mL组患者的胃镜检查时间、操作满意度显著优于达克罗宁8mL组;达克罗宁10mL组泡沫粘附明显减少,黏膜可视度显著增加,优于达克罗宁8mL组,证明达克罗宁剂量与黏膜可视度呈正相关;达克罗宁10mL组患者的消化道病变情况显著少于达克罗宁8mL组,差异均有统计学意义(P<0.05)。结论对接受胃镜检查的患者行检查前口服达克罗宁药物,可有效的缩短检查时间,提高操作满意度,同时还能提高镜下黏膜可视度,达克罗宁剂量越大临床效果越好,结合临床效果和经济指标推荐使用剂量为10mL的达克罗宁药物。
Objective To explore clinical effects of different doses of dyclonine on the effect of gastroscopy for patients.Methods 140 patients who underwent gastroscopy in our hospital from October 2018 to April 2019 were selected as research objects.According to the random number table method,they were divided into the control group(dosage of dyclonine:8mL)and the observation group(dosage of dyclonine:10mL),with 740 cases in each group.Patients in two groups were all given d dyclonine orally within 30 minutes before gastroscopy according to the above ratio.The correlation between different doses of dyclonine and mucosa visibility,gastroscopy time,operation satisfaction and detection of upper gastrointestinal lesions under gastroscopy were compared between two groups.Results The gastroscopy time and operational satisfaction of patients in the dyclonine 10mL group were significantly better than the dyclonine 8mL group.The foam adhesion of dyclonine 10mL group was significantly reduced and mucosal visibility increased significantly,which were better than those in dyclonine 8mL group,demonstrating that dyclonine dose was positively correlated with mucosal visibility.The gastrointestinal lesions of the dyclonine 10mL group were significantly less than those of the dyclonine 8mL group,and the differences were statistically significant(P<0.05).Conclusion Oral administration of dyclonine for patients undergoing gastroscopy can effectively shorten the examination time,improve the operation satisfaction and improve the microscopic mucosal visibility.The greater the dose of dyclonine,the better the clinical effect.A dose of 10mL of dyclonine is recommended in combination with clinical effects and economic indexes.
作者
蔡方梅
王琦
曾红英
CAI Fangmei;WANG Qi;ZENG Hongying(Dongguan Zhangmutou Hospital,Guangdong,Dongguan 523620,China)
出处
《中国医药科学》
2020年第1期103-105,共3页
China Medicine And Pharmacy
