摘要
综合评述了双光子激发的聚集诱导发光(AIE)光敏剂的研究进展,重点讨论了双光子激发的AIE光敏剂的设计思路及在生物医学中的应用,并对其发展前景进行了展望。
The concept of two-photon excited photodynamic therapy based on photosensitizers with aggregation-induced emission( AIE) takes advantages of high penetration depth and precision from two-photon technology,and high photosensitization efficiency in aggregate state from AIE photosensitizers. In this contribution,we review the recent progress in this field,which includes the design principles of two-photon excitable AIE photosensitizers,specific examples of AIE photosensitizers and their biomedical applications.The perspectives for the future development of this field was also discussed.
作者
武文博
刘斌
WU Wenbo;LIU Bin(Department of Chemical and Biomolecular Engineering,National University of Singapore,Singapore 117585,Republic of Singapore)
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
2020年第2期191-203,共13页
Chemical Journal of Chinese Universities
基金
Singapore National Research Foundation Competitive Research Program(No.R279-000-483-281)
National Research Foundation Investigatorship(No.R279-000-444-281)
the National University of Singapore(No.R279-000-482-133)资助
关键词
聚集诱导发光
光敏剂
光动力治疗
双光子激发
Aggregation-induced emission
Photosensitizer
Photodynamic therapy
Two-photon excitation
