摘要
目的探讨腹腔镜胃大部切除术对胃癌患者血清肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)、C反应蛋白(CRP)及并发症的影响。方法选取2017年1月至2019年6月在西昌市人民医院进行手术治疗的100例胃癌患者作为研究对象,根据随机双盲法分为对照组和试验组,每组50例;对照组给予传统开腹手术治疗,试验组给予腹腔镜胃大部切除术治疗,检测两组IL-6、TNF-α及CRP水平,并比较两组并发症发生率。结果试验组术后24 h的IL-6、TNF-α、CRP水平均低于对照组,且并发症发生率低于对照组,差异均有统计学意义(P<0.05)。结论腹腔镜胃大部切除术治疗胃癌患者可降低血清IL-6、TNF-α、CRP水平,降低并发症发生率。
Objective To investigate the effects of laparoscopic subtotal gastrectomy on serum TNF-α,IL-6,CRP and complications in gastric cancer patients.Methods The patients with gastric cancer who were treated by our hospital from January 2017 to June 2019 were divided into control group and experimental group,50 cases in each group according to the random double-blind method.The control group was given traditional open abdominal surgery,and the experimental group was given laparoscopic subtotal gastrectomy.IL-6,TNF-αand CRP levels were measured in two groups,and the incidence of complications was compared.Results Compared with the control group,the indicators of IL-6,TNF-α,and CRP were lower,and the incidence of complications was lower,and the difference was statistically significant(P<0.05).Conclusion Most laparoscopic gastric resection can reduce serum IL-6,TNF-α,CRP levels and reduce complications in gastric cancer patients.
作者
龚国金
殷朝丽
冯泽勇
Gong Guojin;Yin Chaoli;Feng Zeyong(Xichang People's Hospital,Xichang Sichuan 615000,China)
出处
《医疗装备》
2019年第23期13-14,共2页
Medical Equipment
关键词
胃癌
腹腔镜
胃大部切除术
炎症因子
并发症
Gastric cancer
Laparoscopy
Major gastric resection
Inflammatory factors
Complications
