摘要
目的分析常规治疗联合经鼻导管高流量吸氧(HFNC)治疗慢性阻塞性肺疾病急性加重期(AECOPD)患者的临床效果。方法选取2018年1月至2019年4月本院呼吸内科收治的105例AECOPD老年患者作为研究对象,根据不同治疗方式将其分成观察组(53例)和对照组(52例)。对照组患者采用常规对症治疗+无创正压通气(NPPV),观察组患者采用常规对症治疗+HFNC。比较两组的治疗效果。结果治疗5 d时,两组的PaO2、SpO2水平均高于治疗前,PaCO2水平低于治疗前(P<0.05)。治疗5 d时,两组患者的HR、舒张压、收缩压水平均低于治疗前(P<0.05)。治疗5 d时,两组的FEV1/FVC、FEV1%均高于治疗前(P<0.05)。观察组的治疗满意度为86.8%(46/53),显著高于对照组的46.2%(24/52),差异具有统计学意义(P<0.05)。观察组的呼吸治疗平均费用为(40.3±5.7)元/h,显著少于对照组的(60.5±6.9)元/h(P<0.05)。结论常规治疗联合HFNC用于AECOPD患者中具有与NPPV相当的作用,相较之下,患者对于HFNC治疗的满意度更高,且治疗费用更低,值得进一步研究。
Objective To analyze the clinical effect of conventional treatment combined with high-flow nasal cannula(HFNC) in the treatment of patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD). Methods A total of 105 elderly patients with AECOPD admitted in the respiratory medicine department of our hospital from January2018 to April 2019 were selected as the study objects. According to different treatment methods, the patients were divided into observation group(53 cases) and control group(52 cases). The control group was treated with routine symptomatic treatment + non-invasive positive pressure ventilation(NPPV), the observation group was treated with routine symptomatic treatment + HFNC. The therapeutic effects of the two groups were compared. Results At 5 days of treatment, the levels of PaO2 and SpO2 in the two groups were higher than those before treatment, the level of PaCO2 in the two groups were lower than that before treatment(P<0.05). At 5 days of treatment, the levels of HR, diastolic and systolic blood pressure in the two groups were lower than those before treatment(P<0.05). At 5 days of treatment, the FEV1/FVC and FEV1% in the two groups were higher than those before treatment(P<0.05). The treatment satisfaction of the observation group was 86.8%(46/53), which was significantly higher than 46.2%(24/52) of the control group, the difference was statistically significant(P<0.05). The average cost of respiratory therapy in the observation group was(40.3 ±5.7) RMB/h, which was significantly less than(60.5±6.9) RMB/h in the control group(P<0.05). Conclusion Conventional treatment combined with HFNC has the same effect as NPPV in patients with AECOPD. Compared with NPPV, patients are more satisfied with HFNC treatment, and have lower treatment cost, which deserves further study.
作者
廖建军
陆远
LIAO Jian-jun;LU Yuan(Xi'an International Medical Center Hospital,Xi'an 710119;Shenzhen University General Hospital,Shenzhen 518000,China)
出处
《临床医学研究与实践》
2020年第2期53-55,共3页
Clinical Research and Practice
关键词
慢性阻塞性肺疾病
急性加重期
高流量吸氧
经鼻导管
血气指标
chronic obstructive pulmonary disease
acute exacerbation
high flow oxygen inhalation
nasal cannula
blood gas index
