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慢性乙型肝炎及非酒精性脂肪性肝炎患者肝脏病理特征分析 被引量:2

Analysis of pathological characteristics on chronic hepatitis B and nonalcoholic steatohepatitis
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摘要 目的:分析研究非酒精性脂肪性肝炎及慢性乙型肝炎患者肝脏病理特征。方法:选取经过病理证实的非酒精性脂肪性肝炎30例患者和慢性乙型肝炎22例患者为研究对象,将二者病理分解为界面性肝炎、小叶内炎症、汇管区纤维化、窦周纤维化4个特征进行分析。结果:慢性乙型肝炎组患者2级以上界面性肝炎发生率明显高于非酒精性脂肪性肝炎组(100%vs 10%,P<0.001),2级以上汇管区纤维化发生率明显高于非酒精性脂肪性肝炎组(77.2%vs 16.7%,P<0.001)。两组患者小叶内炎症的发生率没有明显差异。结论:慢性乙型肝炎组患者2级以上界面性肝炎和2级以上汇管区纤维化发生率明显高于非酒精性脂肪性肝炎组患者。 Objective:To analyze the pathological features of nonalcoholic steatohepatitis and chronic hepatitis B.Methods:The incidence of Interfacial hepatitis over grade 2 and periportal fibrosis over grade 2 in chronic hepatitis B were significantly higher than nonalcoholic steatohepatitis group(100% vs 10% and 77.2% vs 16.7%, both P<0.001). There was no significant difference in the incidence of lobular inflammation between the two groups. Results:The incidence of Interfacial hepatitis and periportal fibrosis over grade 2 in the chronic hepatitis B were higher than in non-alcoholic steatohepatitis.Conclusion:The incidence of Interfacial hepatitis and periportal fibrosis over grade 2 in the chronic hepatitis B were higher than in non-alcoholic steatohepatitis.
作者 朱永芬 王进 方家追 吕芳芳 ZHU Yong-fen;WANG Jin;FANG Jia-zhui(Department of Hepatology and infection,Shao Yifu Hospital Affiliated to Zhejiang University School of Medicine,Hangzhou Zhejiang,310016,China;不详)
出处 《中西医结合肝病杂志》 CAS 2019年第6期505-506,共2页 Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases
基金 浙江省自然科学基金(No:LY15H030009)
关键词 肝炎 乙型 慢性 非酒精性脂肪性肝炎 界面性肝炎 病理特征 Chronic hepatitis B nonalcoholic steatohepatitis Interfacial hepatitis
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