摘要
目的探讨脑蛋白水解物注射液联合丙戊酸钠防治颅脑创伤后癫痫发作的临床效果。方法选取2016年10月~2018年10月我院收治的439例颅脑创伤患者作为研究对象,根据入院时间将其分为治疗组(220例)和对照组(219例)。治疗组患者入院后即给予脑蛋白水解物注射液和丙戊酸钠联合治疗,对照组患者单用脑蛋白水解物注射液治疗。治疗1个月后,比较两组患者的癫痫总发生率及不良反应发生情况。结果治疗组患者的癫痫总发生率为9.55%,低于对照组的21.46%,差异有统计学意义(P<0.05);治疗组患者的不良反应总发生率为5.00%,低于对照组的10.50%,差异有统计学意义(P<0.05)。结论脑蛋白水解物注射液联合丙戊酸钠对颅脑创伤后的癫痫发作有良好的防治效果,值得临床推广。
Objective To investigate the clinical effect of Cerebroprotein Hydrolysate Injection combined with Sodium Valproate in the prevention and treatment of epilepsy seizures after craniocerebral trauma.Methods A total of 439 patients with craniocerebral trauma admitted to our hospital from October 2016 to October 2018 were selected as research objects.According to the time of admission,the patients were divided into treatment group(220 cases)and control group(219 cases).The treatment group was given Cerebroprotein Hydrolysate Injection and Sodium Valproate after admission.The control group was treated with Cerebroprotein Hydrolysate Injection only.After one month of treatment,the total incidence of epilepsy and adverse reactions were compared between the two groups.Results The total incidence of epilepsy in the treatment group was 9.55%,which was lower than that in the control group(21.46%),the difference was statistically significant(P<0.05).The total incidence of adverse reactions in the treatment group was 5.00%,which was lower than that in the control group(10.50%),and the difference was statistically significant(P<0.05).Conclusion Cerebroprotein Hydrolysate Injection combined with Sodium Valproate has a good prevention and treatment effect on epilepsy seizures after craniocerebral trauma,which is worthy of clinical promotion.
作者
张晓强
周辉
黄小龙
ZHANG Xiao-qiang;ZHOU Hui;HUANG Xiao-long(Department of Neurosurgery,People's Hospital of Guang'an City,Sichuan Province,Guang'an 638000,China)
出处
《中国当代医药》
2020年第1期73-75,共3页
China Modern Medicine
关键词
颅脑创伤
癫痫发作
丙戊酸钠
脑蛋白水解物注射液
Craniocerebral trauma
Epilepsy seizures
Sodium Valproate
Cerebroprotein Hydrolysate Injection
