摘要
目的探讨窒息新生儿心肌酶谱与血钙水平的相关性,为新生儿窒息及继发心肌损伤的临床诊治提供参考。方法便利选取2016年6月—2019年5月该院儿科收治的70例新生儿为研究对象,依据出生Apgar评分不同将入选新生儿分为实验组(窒息新生儿,35例)和对照组(无窒息新生儿,35例),抽取两组静脉血样测定血清Ca与心肌酶谱AST、CK与LDH水平值,比较观察指标差异,线性回顾Ca与心肌酶谱指标相关性。结果实验组血清总钙(2.04±0.76)mmol/L,AST(94.16±32.37)U/L,CK(1273.8±411.93)U/L,LDH(841.7±376.8)U/L,与对照组差异有统计学意义(t=3.116,5.291,16.552,12.681;P<0.05);线性分析窒息新生儿血清Ca与心肌酶谱五项呈显著负相关(r=-0.875,-0.911,-0.902;P<0.05)。结论窒息新生儿血清钙与心肌酶谱存在异常改变,且窒息越严重,血清钙水平越低,心肌酶谱指标越高,两者呈显著负相关,联合监测对患者病情诊断、治疗及预后评估具有参考价值,值得临床推广。
Objective To investigate the correlation between Myocardial Zymogram and serum calcium level in asphyxiated neonates,and to provide reference for clinical diagnosis and treatment of asphyxia neonatorum and secondary myocardial injury.Methods Convenient elected 70 neonates admitted to the hospital from June 2016 to May 2019 were divided into experimental group(35 asphyxiated neonates)and control group(35 non-asphyxiated neonates)according to the birth Apgar score.The levels of serum Ca and AST,CK and LDH of myocardial zymogram were measured with venous blood samples from two groups.The differences of the indexes were compared and the correlation between Ca and myocardial zymogram was linearly reviewed.Results The experimental group had serum total calcium(2.04±0.76)mmol/L,AST(94.16±32.37)U/L,CK(1273.8±411.93)U/L,LDH(841.7±376.8)U/L,and the control group had statistics.Differences(t=3.116,5.291,16.552,12.681;P<0.05);linear analysis of neonatal serum Ca was significantly negatively correlated with myocardial zymogram(r=-0.875,-0.911,-0.902;P<0.05).Conclusion Neonatal serum calcium and myocardial zymogram abnormal changes,the more severe the asphyxia,the lower the serum calcium level,the higher the myocardial zymogram index,the two showed a significant negative correlation,joint monitoring for the patient's disease diagnosis,treatment and prognosis evaluation Value is worthy of clinical promotion.
作者
朱娟
ZHU Juan(Department of Pediatrics,Xiangyang Branch,Jiangsu Provincial People's Hospital,Liyang,Jiangsu Province,213300 China)
出处
《中外医疗》
2019年第34期60-61,97,共3页
China & Foreign Medical Treatment
关键词
新生儿
窒息
心肌酶谱
血清总钙
相关性
Neonates
Asphyxia
Myocardial zymogram
Serum total calcium
Correlation
