摘要
目的观察补阳还五汤联合针刺治疗小儿周围性面瘫的临床疗效。方法选取2012年7月至2017年9月浙江中医药大学附属第一医院针灸科和儿科收治的周围性面瘫患儿40例作为研究对象,按照随机数字表法分为对照组和治疗组,各20例。2组均给予基础治疗,包括泼尼松和阿昔洛韦口服,每日3次。对照组在基础治疗的基础上予针刺患侧翳风、阳白、牵正、颊车、太阳、地仓以及双侧合谷,10 d为1个疗程,疗程间隔2 d。治疗组在对照组治疗方法的基础上予补阳还五汤口服。2组均治疗6~7周后统计疗效。结果对照组总有效率为85.0%,治疗组为95.0%,2组比较,差异有统计学意义(P<0.05)。治疗前,2组血清超氧化物歧化酶(SOD)、丙二醛(MDA)、一氧化氮(NO)水平比较,差异无统计学意义(P>0.05),具有可比性;治疗后,2组SOD、NO水平均较同组治疗前显著升高,MDA水平显著下降,且治疗组升高或下降更显著,差异均有统计学意义(P<0.05)。治疗前,2组House-Brackmann分级量表(HBGS)、Sunnybrook面瘫分级系统(SFGS)评分比较,差异无统计学意义(P>0.05),具有可比性;治疗后,2组HBGS、SFGS评分较同组治疗前均显著升高,且治疗组升高更显著,差异均有统计学意义(P<0.05)。结论补阳还五汤联合针刺治疗小儿周围性面瘫,可显著提高临床疗效,降低氧化应激反应,促进神经功能的恢复,值得临床推广应用。
Objective To observe the clinical efficacy of Buyang Huanwu Tang(补阳还五汤)combined with acupuncture in the treatment of children with peripheral facial paralysis.Methods Forty children with peripheral facial paralysis admitted to acupuncture department and pediatrics department in the First Affiliated Hospital of Zhejiang University of Chinese Medicine from July 2012 to September 2017 were divided into control group and treatment group according to random number table method,with 20 cases in each.The 2 groups were both given basic treatment,including oral administration of prednison and acyclovir,3 times a day.On this basis,the control group was given acupuncture on the affected side Yifeng(TE 17),Yangbai(GB 14),Qianzheng,Jiache(ST 6),Taiyang(EX-HN 5),Dicang(ST 4)and bilateral Hegu(LI 4).Ten days constituted a course of treatment,and the interval between courses was 2 days.On the therapeutic method of the control group,the treatment group was given oral Buyang Huanwu Tang.We kept statistics about the curative effects after the 2 groups were both treated for 6-7 weeks.Results The total effective rate of the control group was 85.0%,that of the treatment group was 95.0%,and the difference between the 2 groups was statistically significant(P<0.05).Before treatment,the difference was not statistically significant in the serum levels of superoxide dismutase(SOD),malondialdehyde(MDA)and nitric oxide(NO)between the two groups(P>0.05),and they were comparable.After treatment,the levels of SOD and NO in the two groups all significantly increased compared with the same group before treatment,while the level of MDA significantly decreased,moreover,the treatment group increased or decreased more significantly,and the difference was statistically significant(P<0.05).Before treatment,the difference was not statistically significant in scores of House-Brackmann grading scales(HBGS)and Sunnybrook facial paralysis grading systems(SFGS)between the two groups(P>0.05),and they were comparable.After treatment,the scores of HBGS
作者
阮俊
RUAN Jun(School of Postgraduate,Zhejiang University of Chinese Medicine,Hangzhou,Zhejiang,310053,China)
出处
《中医儿科杂志》
2019年第6期91-94,共4页
Journal of Pediatrics of Traditional Chinese Medicine
关键词
周围性面瘫
小儿
针刺
补阳还五汤
临床观察
peripheral facial paralysis
children
acupuncture
Buyang Huanwu Tang(补阳还五汤)
clinical observation
