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乳腺神经鞘瘤的诊治进展

Progress of the diagnosis and treatment in nerve sheath tumors of the breast
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摘要 目的对乳腺神经鞘瘤进行再认识,以提高其诊断率及治愈率。方法检索乳腺神经鞘瘤的相关文献,对该病的起源、病因、临床表现、影像学特点、病理学特点、治疗及预后的相关知识进行分析并综述。结果乳腺神经鞘瘤十分罕见,起源于神经鞘膜雪旺细胞,其具体病因不明且临床表现无特异性,与其他乳腺疾病之间难以鉴别,如叶状囊肉瘤、乳腺血管外皮细胞瘤、乳腺纤维腺瘤等。影像学资料可提供一定的参考价值,但金标准依赖于病理学及免疫组织化学检查。手术能治愈良性乳腺神经鞘瘤,但有恶变可能,须术后随访。恶性神经鞘瘤以手术切除为主,辅以放化疗,可有效预防肿瘤局部复发和远处转移。乳腺神经鞘瘤的预防可参考乳腺癌筛查。结论临床实践中需了解乳腺神经鞘瘤的诊断与治疗,争取做到早发现、早诊断和早治疗,提高该病的诊断率及治愈率,以保护女性的身心健康。 Objective To re-understand the nerve sheath tumors of the breast, to improve its diagnosis and cure rate. Method Searched the relevant literatures of nerve sheath tumors of the breast, to analyze and summarize the origin,etiology, clinical manifestations, imaging characteristics, pathological characteristics, treatment, and prognosis of this disease. Results Nerve sheath tumors of the breast was a very rare disease, which originated in the neuromembrane Snowwang cells. its specific cause was unknown and clinical manifestations were not specific, and other breast diseases were difficult to identify, such as leaf ybrilloma, mammary vascular epidermal cytoma, breast fibroids, and so on. Imaging data could provide some reference value, but the gold standard relied on pathology and immunohistochemical examination. Surgery could cure benign nerve sheath tumors of the breast, but there was a possibility of malignant changes that required follow-up after surgery. Malignant neuroblastoma was mainly surgically removed, supplemented by chemotherapy, which could effectively prevent the recurrence of tumor and distant metastasis. The prevention of nerve sheath tumors of the breast could be referred to breast cancer screening. Conclusions During clinical practice, we need to understand the diagnosis and treatment of nerve sheath tumors of the breast to achieve early detection, early diagnosis, and early treatment, as well as improve the diagnosis rate and cure rate of the disease, in order to protect women’s physical and mental health.
作者 任航军 姜昌镐 REN Hangjun;JIANG Changgao(Department of General Surgery,The Affiliated Hospital of Yanbian University,Yanji,Jilin 133000,P.R.China)
出处 《中国普外基础与临床杂志》 CAS 2020年第1期123-126,共4页 Chinese Journal of Bases and Clinics In General Surgery
关键词 乳腺神经鞘瘤 起源 病因 临床表现 治疗 综述 nerve sheath tumors of the breast origin etiology clinical manifestation treatment review
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