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关节镜微骨折术联合腓骨截骨对内翻性膝关节骨性关节炎疗效及血清IL-1β、IL-6、TNF-α的影响 被引量:17

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摘要 目的分析关节镜微骨折术联合腓骨截骨对内翻性膝关节骨性关节炎疗效及血清白细胞介素-1β(IL-1β)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)的影响。方法选取自2015-02—2017-05收治的内翻性膝关节骨性关节炎96例,根据治疗方法不同分为2组。对照组给予关节镜微骨折术治疗,观察组给予关节镜微骨折术联合腓骨近端截骨治疗,分析2组治疗后的临床疗效。结果2组术前IL-1β、IL-6、TNF-α水平组间比较,差异无统计学意义(P>0.05)。观察组术后4周时IL-1β、IL-6、TNF-α水平低于对照组,差异有统计学意义(P<0.05)。2组术前美国特种外科医院膝关节评分(HSS)评分、疼痛VAS评分、胫股关节间隙角(JS角)、股骨胫骨角(FT角)组间比较,差异无统计学意义(P>0.05)。观察组12个月后HSS评分高于对照组,疼痛VAS评分及JS角、FT角低于对照组,差异有统计学意义(P<0.05)。结论关节镜微骨折术联合腓骨截骨治疗内翻性膝关节骨性关节炎可降低关节液内炎症因子的表达,改善膝关节功能。
出处 《中国骨与关节损伤杂志》 2019年第12期1299-1301,共3页 Chinese Journal of Bone and Joint Injury
基金 河北省沧州市科技支撑计划项目(172302071)
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