摘要
目的观察加用通络外治法治疗瘀血阻滞型膝骨关节炎(KOA)的临床疗效。方法将60例瘀血阻滞型KOA患者按照随机数字表法分为2组。对照组30例予硫酸氨基葡萄糖胶囊治疗;治疗组30例在对照组治疗基础上加用通络外治法(中药热奄包外敷、刺络放血和局部拍打)治疗。2组疗程均为6周。治疗3、6周后对中医症状疗效、疼痛视觉模拟评分法(VAS)评分、西安大略湖和麦克马斯特大学(WOMAC)骨关节炎指数评分进行评估;比较2组治疗前后红细胞沉降率(ESR)、C反应蛋白(CRP)变化。结果治疗3周后,治疗组总有效率83.33%,对照组总有效率50.00%;治疗6周后,治疗组总有效率96.67%,对照组总有效率86.67%。治疗组治疗3、6周后中医症状疗效均优于对照组(P<0.05)。治疗组治疗3、6周后疼痛VAS评分均较本组治疗前降低(P<0.05),对照组治疗6周后疼痛VAS评分较本组治疗前降低(P<0.05);治疗组治疗3、6周后疼痛VAS评分均低于对照组治疗同期(P<0.05)。治疗组治疗3、6周后WOMAC骨关节炎指数各项评分均较本组治疗前降低(P<0.05),对照组治疗6周后WOMAC骨关节炎指数各项评分较本组治疗前降低(P<0.05);治疗组治疗3、6周后WOMAC骨关节炎指数评分各项均低于对照组治疗同期(P<0.05)。2组治疗前后ESR、CRP组内比较差异均无统计学意义(P>0.05),2组治疗后ESR、CRP组间比较差异无统计学意义(P>0.05)。结论加用通络外治法治疗瘀血阻滞型KOA,能明显降低患者疼痛VAS评分、WOMAC骨关节炎指数评分,改善关节疼痛、僵硬、活动不利及局部脉络青紫或迂曲怒张等症状,其临床疗效优于单纯应用硫酸氨基葡萄糖口服治疗。
Objective To observe the effect of Tongluo external therapy in the treatment of knee osteoarthritis(KOA) with blood stasis block type. Methods 60 patients with KOA were divided into two groups according to the random number table method. 30 cases in control group were treated with glucosamine sulfate capsule. 30 cases in treatment group were treated by Tongluo external therapy(external application of Reranbao, blood letting and local beating) on the basis of the control group. The course of treatment was 6 weeks in both groups. After 3 and 6 weeks of treatment, the therapeutic effect of traditional Chinese medicine, the score of pain visual analogue(VAS), the score of osteoarthritis index of Western Ontario and McMaster University(WOMAC) were evaluated;the changes of erythrocyte sedimentation rate(ESR) and C-reactive protein(CRP) before and after treatment were compared between the two groups. Results After 3 weeks of treatment, the total effective rate was 83.33% in treatment group and 50.00% in control group. After 6 weeks of treatment, the total effective rate was 96.67% in treatment group and 86.67% in control group. The curative effect of TCM symptoms in the treatment group was better than that in the control group after 3 and 6 weeks of treatment(P<0.05). The VAS score of pain in the treatment group after 3 and 6 weeks of treatment were lower than that before treatment(P<0.05). The VAS score of pain in the control group after 6 weeks was lower than that before treatment(P<0.05). The VAS score of pain in the treatment group was lower than that in the control group after 3 and 6 weeks of treatment(P<0.05). The scores of WOMAC osteoarthritis in the treatment group after 3 and 6 weeks of treatment were lower than that before treatment(P<0.05). The scores of WOMAC osteoarthritis in the control group after 6 weeks was lower than that before treatment(P<0.05). The scores of WOMAC osteoarthritis in the treatment group was lower than that in the control group after 3 and 6 weeks of treatment(P<0.05). There was no si
作者
张宁
霍珍
罗亚萍
潘利敏
侯小双
冯媛媛
马琳
ZHANG Ning;HUO Zhen;LUO Yaping(Hebei University of Chinese Medicine,Shijiazhuang,Hebei 050091)
出处
《河北中医》
2019年第11期1627-1631,1636,共6页
Hebei Journal of Traditional Chinese Medicine
基金
河北省政府资助临床医学优秀人才培养和基础课题研究项目(编号:2017043637)
石家庄市科学技术与发展指导计划课题(编号:111461123)
关键词
骨关节炎
膝
辨证分型
中医外治
Osteoarthritis,knee
Syndrome differentiation
External treatment of traditional Chinese medicine
